Novel tiopronin freeze drying powder preparation and its prepn. process

Abstract

A freeze-dried powder injection of tiopronin is prepared from tiopronin and the human body receptable non-active carrier chosen from dextran, glucose, mannitol, xylitol, lactose, amino acid, etc through preparing liquid medicine, regulating pH value, removing heat source and bacteria, filling in bottles and freeze drying.

Description

technical field

[0001] The tiopronin freeze-dried powder preparation and preparation method involved in the present invention aim to provide a stable freeze-dried powder preparation and a simple preparation method thereof, so as to overcome the cumbersome preparation process and relatively high production cost of the existing freeze-dried powder preparation. Shortcomings of instability of tiopronin in Gaoheshui injection preparations. The preparation method of the freeze-dried powder preparation is as follows: after dissolving the medicine, adding an appropriate protective agent, adjusting the pH value of the medicine solution to a range acceptable to the human body, and then freeze-drying to form a loose block. When the preparation is used clinically, it can be directly dissolved and diluted with physiological saline, and no proprietary solvent is required. technical background

[0002] Tiopronin is a metabolic improving regulator mainly used to ...