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Medication composition for treating liver disease

A liver disease and composition technology, which is applied in the field of pharmaceutical compositions composed of two raw materials of total iridoid glycosides, can solve the problems of unclear material basis of preparations, low extraction rate of effective parts, and many clinical adverse reactions. Significant synergistic effect, significant curative effect, guaranteed clinical efficacy

Inactive Publication Date: 2006-12-06
成都迅科医药科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In addition, the existing preparation process of Astragalus and Gardenia generally adopts the method of water extraction and alcohol precipitation, and there is no report on the effective part of the drug. The traditional extraction method has a low extraction rate, little content and large loss of the effective part, and there are preparation substances Unclear basis, unreasonable quality control, poor drug stability, large fluctuations in curative effect, and many clinical adverse reactions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Example 1: Total iridoid glycosides of Gardenia jasminoides-total astragalus saponins soft capsule

[0052] Component Weighing

[0053] Total Astragalus Saponins 50g

[0054] Gardenia Total Iridoid Glycosides 10g

[0055] Vegetable oil 240g

[0056] Preparation process: Mix the total iridoid glycosides of Gardenia jasminoides, total astragalus saponins and vegetable oil, use gelatin as the capsule shell material, and use the existing soft capsule preparation process to make 1000 soft capsules to obtain 5 parts of total astragalus saponins and 1 soft capsule formulation of gardenia total iridoid glycosides.

Embodiment 2

[0057] Example 2: Total iridoid glycosides of Gardenia Fructus-Total Astragalus Saponins Tablets

[0058] Component Weighing

[0059] Gardenia Total Iridoid Glycosides 60g

[0060] Total Astragalus Saponins 12g

[0061] Dextrin 78g

[0062] Starch 100g

[0063] Preparation process: Take total iridoid glycosides of Gardenia jasminoides, total saponins of astragalus, dextrin and starch, mix evenly, granulate, sieve, dry, and press into 1000 pieces, that is, the total iridoids containing 5 parts of Gardenia jasmine glycosides and 1 tablet of total astragalosides.

Embodiment 3

[0064] Example 3: Total iridoid glycosides of Gardenia glycosides-total saponins of astragalus freeze-dried powder for injection

[0065] Component Weighing

[0066] Gardenia Total Iridoid Glycosides 30g

[0067] Total Astragalus Saponins 10g

[0068] Mannitol 200g

[0069] Preparation process: Dissolve the total iridoid glycosides of Gardenia jasminoides, total saponins of astragalus and mannitol in 2000ml of water for injection, filter, sub-package into 1000 bottles, and freeze-dry using the existing lyophilized powder injection preparation process to obtain 3 parts Freeze-dried powder injection of total iridoid glycosides of gardenia and 1 part of total saponins of astragalus.

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PUM

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Abstract

A Chinese medicine for preventing and treating the hepatism (such as hepatitides, hepative injury, etc) is prepared from capejasmine fruit and astragalus root. It contains the iridoid glycoside extracted from capejasmine fruit and the general astragalus saponin.

Description

Technical field [0001] The invention relates to a pharmaceutical composition for treating liver diseases, which belongs to the technical field of medicine, and is specifically a pharmaceutical combination composed of two raw materials: total saponins extracted from the traditional Chinese medicine Astragalus and total iridoid glycosides extracted from the traditional Chinese medicine Gardenia things. Background technique [0002] Liver disease is a common and frequently-occurring disease at present, involving a wide range of diseases, including various acute and chronic hepatitis, cirrhosis, liver tumors, liver damage caused by various physical and chemical reasons, etc. [0003] The theory of traditional Chinese medicine believes that the occurrence of disease is a process of the struggle between good and evil. Due to the complicated pathogenesis of liver disease, the course of the disease is generally long and the outcome is changeable. The liver and gallbladder are exter...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61K31/7048A61K9/08A61K9/14A61K9/16A61K9/22A61K9/48A61K9/20A61P1/16
Inventor 罗红梅
Owner 成都迅科医药科技有限责任公司
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