Chewing gum possessing tooth cleaning effect and a teeth cleaning method

Inactive Publication Date: 2006-08-17
GUMLINK AS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0010] An object of the present invention is to provide

Problems solved by technology

During the brushing of teeth with a toothbrush, the toothbrush bristles push against the gingiva and cause exposure of the innermost portion of the tooth side surface.
This portion is weak in a mechanical sense because the enamel is thin or even missing i

Method used

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  • Chewing gum possessing tooth cleaning effect and a teeth cleaning method
  • Chewing gum possessing tooth cleaning effect and a teeth cleaning method

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0167] The chewing gum in the following example was manufactured from commercially available gum base (Danfree, available from Gumlink A / S, Vejle, Denmark) mixed with sweeteners, taste ingredients and active ingredients. The chewing gum was manufactured as a two-layer product and the gum material for the two layers was produced with the following ratios:

[0168] Formulation 1:

Gum base60.00%Sorbitol18.20%Peppermint powder1.50%Menthol powder0.30%Dicalciumphosphate2.70%Green tea5.00%Baking soda0.40%Calcium carbonate4.10%Calcium pyrophosphate6.50%Succralose0.25%Magnesium stearate0.50%Eucalyptus powder0.50%

[0169] Formulation 2:

Gum base30.00%Xylitol68.80%Peppermint powder0.50%Menthole powder0.20%Magnesium stearate0.50%

[0170] The gum base was granulated (GALA underwater pelletizer) to form granules with diameters in the range of approximately 0.5-1.5 mm and mixed with the active ingredients.

[0171] The particulate mixture of formulation 1 (1.5 g) was filled into a tablet pressing machin...

example 2

Study for Assessing Oral Malodor

[0187] The purpose of this study was to demonstrate the efficacy of chewing gum containing green tea extract and zinc in reducing oral malodor (OM) as compared to a placebo.

Methods & Materials:

[0188] The investigation was a longitudinal study, which determined efficacy of the chewing gum in reducing oral malodor. A total of 20 subjects with self proclaimed oral malodor (OM) that has been verified by an organoleptic judge (OJ) were selected for this randomized clinical trial. Subjects were instructed to chew the provided gum five times a day for 20 minutes each time for a period of seven days.

[0189] Qualified subjects completed a demographic and a medical history survey and were assessed for degrees of OM. The qualifying score of the subjects as determined by self-proclamation and OJs was minimum of 2 or above on the 5-point malodor scale. Baseline (day 0) and post treatment (day 7) examinations included: 1) organoleptic tests 2) oral soft tissue ...

example 3

Study for Assessing Re-mineralization

Materials and Methods:

Demineralization Solution Preparation:

[0206] The demineralizing buffer solutions was made up of analytical-grade chemicals and deionized water. It contained 2.2 mM CaCl2, 2.2 mM NaH2PO4, 0.05 M acetic acid and pH was adjusted with 1 M KOH to 4.4.

Artificial Enamel Carious Lesion Formation:

[0207] Sound extracted molars were cleaned of any soft tissue debris and inspected for cracks, hypoplasia, and white spot lesions under the stereomicroscope. The teeth were then coated with acid-resistant varnish (Lancester, Germany), leaving a narrow ‘window’, approximately 1 mm wide, on the sound, intact surface of the buccal and / or lingual enamel. Each tooth was immersed, for 96 hours, in 10 ml of demineralizing solution in order to produce lesions of about 130-180 μm deep. The teeth were sectioned longitudinally through the lesions, approximately 100-150 μm thick, by a hard tissue microtome (Leica 1600, Wetzlar, Germany). Seventy...

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Abstract

The invention relates to a chewing gum possessing tooth cleaning effects, excluding the tooth brush abrasive effect, which chewing gum when chewed on a daily basis as a tooth cleaning agent is capable of replacing the daily tooth brushing, whereby abrasive cleaning damages on teeth side surfaces and gingiva are avoided.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] The present application claims the benefit of priority from European Patent Application No. 05388006.8 filed on Jan. 28, 2005 and from European Patent Application No. 05388007.6 filed on Jan. 28, 2005. STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] Not Applicable REFERENCE TO A MICROFICHE APPENDIX [0003] Not Applicable BACKGROUND OF THE INVENTION [0004] The present invention relates to a chewing gum possessing tooth cleaning effects. [0005] Chewing gum suitable for temporary tooth cleaning is known. Such chewing gum is e.g. disclosed in the U.S. Pat. Nos. 5,380,530; 5,693,334; 6,365,130; and US patent publication No. 2004 / 0115247 A1. These types of chewing gum have only been capable to demonstrate a limited capacity for tooth cleaning for single day use or at the most for use during a few days when a toothbrush is accidentally not available. After such a day a thorough cleaning with toothbrush and toothpaste has ...

Claims

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Application Information

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IPC IPC(8): A61K9/68
CPCA61K8/97A61Q11/00A61K8/9739A61K8/9789A61P29/00A61P31/04
Inventor KRISTIANSEN, TOVE NORDESTGAARDGYLDENVANG, LARSMIKKELSEN, RIKKE
Owner GUMLINK AS
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