Natural topical compositions for the prevention and treatment of diaper rashes and related conditions

Abstract

The treatment and prevention of skin irritations, including diaper rash, is facilitated with the topical application of cranberry anthocyanins in a cosmetically acceptable vehicle.

Description

BACKGROUND OF THE INVENTION[0001]1. Field of the Invention[0002]This invention relates to topical compositions for the treatment of skin irritation and, more particularly, to anthocyanin-containing compositions for the treatment of diaper rash.[0003]2. Background of the Invention and Related Art[0004]Diaper rash (also referred to as diaper dermatitis or incontinence dermatitis) is a generic term applied to rashes seen in the diaper area (genital, buttocks and thighs, or any area of skin that is covered by a diaper-like dressing) that may be caused by a variety of skin disorders. Diaper dermatitis develops when skin is exposed to prolonged wetness, increased skin pH caused by urine and feces, with the resulting breakdown of the stratum corneum, or outermost layer of the skin. In adults, the stratum corneum is composed of 25 to 30 layers of flattened dead keratinocytes, which are continuously shed and replaced from below. These dead cells are interlayered with lipids secreted by the s...

AI Technical Summary

Benefits of technology

[0009]The present invention addresses a number of problems associated with previously known diaper rash treatments by providing compositions which include anthocyanins which contribute to the treatment and / or prevention of diaper rash. While previous treatments and compositions required multiple ingredients to achieve a) a reduction of pH, b) a reduction of moisture and c) a reduction of irritant microbes and / or irritant microbial byproducts, the inclusion of at least one anthocyanin in the composition of the present invention achieves all of these objectives. And given that vaccinium macrocarpon known colloquially as cranberry, which contains the preferred anthocyanins for use in the present invention is widely abundant and inexpensive, the present invention, achieves the aforementioned objectives in a very cost-effective manner.

[0011]Cranberry and / or cranberry extract is naturally acidic and therefore naturally helps to lower skin pH. Cranberry has also been found to contain as much as 12% fiber (DUKE1992A), and is a known moisture adsorbent. And, most importantly, numerous studies (Di Martino et al. 2006, Firon et al. 1987; Jepson et al. 2004; Howell et al. 2005; Raz et al. 2004; Tsukada et al. 1994; Turner et al. 2005; Zafriri et al., 1989; Zhang et al. 2005) have shown that cranberry and / or cranberry extracts inhibit the adhesion of yeast and bacteria to epithelial surfaces. Such inhibition of adhesion inhibits the growth of yeast and bacteria (as well as other microorganisms). With reduced adhesive capacity, microorganisms are more easily removed through common practices of diaper changing, wiping and general good hygiene. Thus, cranberry and / or cranberry extract contributes many attributes, which effectively combat many of the causal factors of diaper rash.

Problems solved by technology

In infants, this layer of the skin is much thinner and more easily disrupted.