Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders

a technology of compositions and topiramate, applied in the direction of drug compositions, antibacterial agents, metabolic disorders, etc., can solve the problems of obesity, shortness of breath, and substantial increase in the risk of morbidity from hypertension, so as to reduce the side effects of bupropion and reduce the exposure
US20090304789A1Inactive Publication Date: 2009-12-10VIVUS
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
VIVUS
Publication Date
2009-12-10
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is drawn to novel topiramate compositions as well as methods for treating obesity and related conditions, including conditions associated with and / or caused by obesity per se. The present invention also features a pharmaceutical composition that includes, e.g., topiramate alone or in combination with a sympathomimetic agent and a novel escalating dosing strategy for administering such compositions.
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Description

BACKGROUND

[0001] The prevalence of obesity in both children and adults is on the rise in first world countries, especially in the United States, as well as in many developing countries such as China and India. Many aspects of a person's life are affected by obesity, from physical problems such as knee and ankle joint deterioration, to emotional problems resulting from self-esteem issues and society's attitude towards heavy people. The medical problems caused by obesity can be serious and often life-threatening and include diabetes, shortness of breath and other respiratory problems, gallbladder disease, hypertension, dyslipidemia (for example, high cholesterol or high levels of triglycerides), cancer, osteoarthritis, other orthopedic problems, reflux esophagitis (heartburn), snoring, sleep apnea, menstrual irregularities, infertility, gout, problems associated with pregnancy, heart trouble, muscular dystrophy and metabolic disorders, including hypoalphalipoproteinemia, familial combi...

Claims

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