3 results about "Caffeic acid phenethyl ester" patented technology

The invention discloses the technical field of biological medicine, and particularly relates to application of caffeic acid phenethyl ester in preparation of a ribosome large subunit protein L1 targeted inhibitor. According to the present invention, the drug affinity induced target stability discovers that the ribosome large subunit protein L1 target inhibitor can directly target the ribosome large subunit protein L1 in bacteria, and can be adopted as the competitive inhibitor to competitively combine with the RRF L1 so as to inhibit the ribosome recovery process, such that the bacterial translation process is inhibited, and the bacterial protein synthesis blocking and death are caused. The mechanism enables the ribosome large subunit protein L1 to become a ribosome target with therapeutic potential, provides a new target and theoretical basis for clinical treatment of bacterial infection, and provides new support for screening of new broad-spectrum antibiotics.

A method of treating acne, of treating UV or radiation induced injury, of reducing the appearance of scars, and / or of treating mucositis, including topically applying a composition including CAPE to a human or other mammal in need thereof, in a therapeutically effective amount and / or from about 1% to about 50% CAPE by weight.

The invention belongs to the field of pharmaceutical preparations. The invention relates to a calcium alginate microsphere containing chitosan oligosaccharide coated bifidobacterium and caffeic acid phenethyl ester nano-enzyme and a preparation method of the calcium alginate microsphere. The calcium alginate microspheres containing the chitosan oligosaccharide coated bifidobacterium and the caffeic acid phenethyl ester nano-enzyme prepared by the preparation method disclosed by the invention can be used for remarkably reducing the uric acid level of rats with gouty arthritis and alleviating the joint swelling of the rats with gouty arthritis.