6 results about "Caffeic acid phenethyl ester" patented technology

The invention discloses the technical field of biological medicine, and particularly relates to application of caffeic acid phenethyl ester in preparation of a ribosome large subunit protein L1 targeted inhibitor. According to the present invention, the drug affinity induced target stability discovers that the ribosome large subunit protein L1 target inhibitor can directly target the ribosome large subunit protein L1 in bacteria, and can be adopted as the competitive inhibitor to competitively combine with the RRF L1 so as to inhibit the ribosome recovery process, such that the bacterial translation process is inhibited, and the bacterial protein synthesis blocking and death are caused. The mechanism enables the ribosome large subunit protein L1 to become a ribosome target with therapeutic potential, provides a new target and theoretical basis for clinical treatment of bacterial infection, and provides new support for screening of new broad-spectrum antibiotics.

The invention discloses a female private care gel with multiple effects and a preparation method thereof. The gel is prepared from the following components: carbomer 980, palmitoyl 3 peptide, phenethyl caffeate, glycerol, pentanediol, sodium hyaluronate, hydrolyzed sodium hyaluronate, panthenol, glycerol glucoside, crithmum maritimum callus fermentation filtrate, lysozyme, an ecological nutrient solution and the balance of water. According to the female private care gel disclosed by the invention, through a scientific formula and a reasonable preparation process, the synergistic effect of all the components is fully exerted, the use limitation of palmitoyl 3 peptide in vaginal gel is effectively solved, and the gel can better adapt to the vaginal environment, promote the production of collagen and realize the effects of tightening and moisturizing. Meanwhile, the product has multiple effects of repairing in vitro, moisturizing, relieving, resisting inflammation, regulating flora balance and the like, comprehensively cares female private health, and has a wide market application prospect.

A method of treating acne, of treating UV or radiation induced injury, of reducing the appearance of scars, and / or of treating mucositis, including topically applying a composition including CAPE to a human or other mammal in need thereof, in a therapeutically effective amount and / or from about 1% to about 50% CAPE by weight.

The invention relates to a caffeic acid phenethyl ester derivative as well as a preparation method and application thereof. The compound provided by the invention is (E)-3-(3, 4-dihydroxyphenyl)-N-phenethyl acrylamide by using an IUPAC standard naming method, has been proved to have a good anti-tumor effect, and can effectively inhibit proliferation of various tumor cells. The invention also relates to a preparation method of the compound and application of the compound in preparation of medicines for preventing and / or treating tumors.

Compositions and methods for treating Obstructive Sleep Apnea (OSA)-associated atherosclerosis comprising administering to a subject in need thereof an effective amount of a bile salt hydrolase (BSH) inhibitor such as caffeic acid phenethyl ester

The invention belongs to the field of pharmaceutical preparations. The invention relates to a calcium alginate microsphere containing chitosan oligosaccharide coated bifidobacterium and caffeic acid phenethyl ester nano-enzyme and a preparation method of the calcium alginate microsphere. The calcium alginate microspheres containing the chitosan oligosaccharide coated bifidobacterium and the caffeic acid phenethyl ester nano-enzyme prepared by the preparation method disclosed by the invention can be used for remarkably reducing the uric acid level of rats with gouty arthritis and alleviating the joint swelling of the rats with gouty arthritis.