The embodiment of the invention discloses a camera group calibration method and device, equipment and a medium, and relates to the technical field of camera calibration. The method comprises the following steps: acquiring a calibration object image of a to-be-calibrated object in a candidate camera coordinate
system, and determining candidate calibration object coordinates in the candidate camera coordinate
system according to the calibration object image; judging whether the candidate camera coordinate
system is a reference camera coordinate system or not, and if not, converting the candidate calibration object coordinates under the candidate camera coordinate system into reference calibration object coordinates under the reference camera coordinate system according to a preset camera
group transformation matrix; according to the reference calibration object coordinate and a preset
calibration error function, determining corresponding calibration compensation data, and according to the reference calibration object coordinate and the calibration compensation data, determining a target calibration object coordinate of the object to be calibrated; wherein the
calibration error function is determined based on sphere images of the calibration sphere at different acquisition positions in the view field overlapping area of the camera group and a preset sphere
radius. And the space consistency and robustness of camera group calibration are improved.