31results about "Investigating sterilization degree" patented technology

A pathogen surrogate, formed by a DNA tag or bar code and a carrier, is described for use in the validation and verification of sanitation, such as in food processing operations and for wash water systems for fresh produce. The carrier material is selected so that the pathogen surrogate mimics the behavior of a pathogen when subjected to a sanitation operation. One or more surrogates can be introduced in to an environment, which is then subjected to sanitation process, followed by a detection process using the DNA tag of the surrogate.

A process indicator isolation chamber includes a housing having an interior volume; an inlet at a first end of the housing; an opening at a second end of the housing; and a flange extending radially outward from the housing. A removable module includes: a frame removably disposed in the interior volume, the removable module including a first end disposed in the interior volume; a shielding cap attached to the frame at a second end of the removable module, the shielding cap including a top portion that covers the opening of the housing and a side portion that covers a portion of an outer surface of the housing between the flange and the second end; and a process indicator mount attached to the frame and disposed in the interior volume. A tortuous outlet passage is formed between the cap and outer surface of the housing when the removable module is installed.

To provide a test soil which can be attached directly to an object to be cleaned and is visually detectable.SOLUTION: Disclosed is a test soil comprising a plurality of molecules of labeled polypeptides, where the labeled polypeptide is a polypeptide to which a dye is added by a covalent bond, and the value of X calculated by the following formula is 100,000 or more: X=(number of dyes comprised in one molecule of labeled polypeptide)×(molar absorption coefficient of dye (M-1 cm-1)).SELECTED DRAWING: Figure 7

A sterilization challenge device for verifying the efficacy of a gas sterilization process includes an outer container, an inner container, and a cap. The outer container includes an open end, a closed end, a chamber configured to contain the inner container for containing a chemical indicator, and at least one hole arranged proximate the open end. The cap is configured to engage with the outer container to close the open end, and the at least one hole is configured to provide a flow path for the gaseous sterilant into the chamber.

A sterilization challenge device for verifying the efficacy of a gas sterilization process includes an outer container, an inner container, and a cap. The outer container includes an open end, a closed end, a chamber configured to contain the inner container for containing a chemical indicator, and at least one hole arranged proximate the open end. The cap is configured to engage with the outer container to close the open end, and the at least one hole is configured to provide a flow path for the gaseous sterilant into the chamber.

To provide UV-responsive laminates including a first layer having a photochromatic pigment arranged as a pigment texture, or one or more photochromatic indicators, or combinations thereof.SOLUTION: The photochromatic pigment may be disposed on the laminates during laminate fabrication, prior to laminate installation, or subsequently to the installation in situ. The photochromatic pigment is configured to change from a first state to a second state in response to exposure to an ultraviolet (UV) light source, the first state is invisible to the naked eye under ambient lighting and the second state is visible to the naked eye under ambient lighting. The UV-responsive laminates may further include additional layers, such as a second layer which may be a coupling layer configured to removably couple the laminate to a component. Additional layers, such as a protective layer or a backing layer, may also be included in the UV-responsive laminate.SELECTED DRAWING: Figure 1D

A method of marking a residual aqueous contaminant on a surface to be decontaminated comprises first mixing a first part of a marking system with a second part of the marking system, wherein the first part of the marking system comprises a pH-sensitive dyestuff and has a first pH, and exhibits a first colour, and the second part of the marking system comprises a pH modifier. Upon mixing the first and second parts of the marking system, a marker composition is obtained that has a second pH and exhibits a second colour, different to the first colour. The method further comprises applying the marker composition to the surface, such that the marker composition changes colour from the second colour to a third colour, different to the second colour, when in contact with a residual aqueous contaminant on the surface having a pH that differs from the second pH, thereby marking the position of the contaminant with the third colour.

A disinfectant visualizing sheet includes a base material, a chromogenic portion disposed on the base material, and a coating portion on the chromogenic portion, wherein the chromogenic portion includes a visualizing agent that changes a color state thereof upon exposure to a disinfectant, and wherein the coating portion has a silsesquioxane structure.

A sterilization challenge device for verifying the efficacy of a gas sterilization process includes an outer container, an inner container, a chemical indicator, and a cap. The outer container includes an open end, a closed end, a chamber configured to contain the inner container containing the chemical indicator, and at least one hole arranged proximate the open end. The cap is configured to engage with the outer container to close the open end, and the at least one hole is configured to provide a flow path for the gaseous sterilant into the chamber.

The invention discloses a sterilisation test pack. The sterilisation test pack may include: a housing defining an indicator compartment having a volume; a channel extending between the compartment opening and the external opening, the channel being in fluid communication with the indicator compartment through the compartment opening, and the ambient atmospheric environment being in fluid communication with the channel through the external opening such that the indicator compartment is in fluid communication with the ambient atmospheric environment through the channel, the channel has a length measured between the compartment opening and the outer opening and a hydraulic radius along the length; and an indicator disposed in the indicator compartment, wherein the ratio of the volume of the compartment to the hydraulic radius of the channel may be in the range of 1000 cm2 to 8000 cm2.

In some embodiments, a sensor device includes a first electrode and a second electrode, each of the first and second electrodes being electrically coupled to an electrical bridge. The electrical bridge includes a conductive polymer having a first impedance state and a second impedance, the second impedance state being different than the first impedance sate. The sensor device also includes a latent base.

An example sterilization indicator (102) includes a cover (122), an indicator (102), and a seal (142). The cover (122) defines at least a portion of a cavity (138). The indicator (102) is disposed within the cavity (138). The indicator (102) is configured to fluidly couple with an internal cavity (110) of a sterilization package (package) and indicate an exposure to a sterilant. The seal (142) is configured to form a microorganism barrier between an exterior of the cover (122) and an internal cavity (110) of a sterilization package (100).

Marker composition comprising water, 1-10 wt.% non-ionic surfactant selected from alkyl polyglucosides, alcohol ethoxylates and alcohol ethoxylate propoxylates, or mixtures thereof, 1-5% organic solve

The present disclosure provides embodiments of a sterilization indicator reading apparatus. The sterilization indicator reading apparatus includes a plurality of wells disposed in a housing configured to receive a plurality of biological indicators. Each well includes a heater sleeve that is thermally coupled within and configured to rapidly heat a biological indicator and provide rapid results of the effectiveness of a sterilization process. The heater sleeve is communicatively coupled with a printed circuit board that controls the heating profile of a biological indicator depending on the desired heating time and desired temperature to provide rapid results of the effectiveness of a sterilization process.

A method for signifying a selected cumulative scrubbing action between a device and a surface, the cumulative scrubbing action being signified by a signaling element, wherein the signaling element is configured to provide an observable signal when the selected cumulative scrubbing action has been provided to the surface. The method may comprise applying scrubbing action to the signaling element to release and / or expose at least a first portion of an indicator, and observing the device and / or surface for the signal. The present disclosure also relates to signaling elements and devices for use according to the methods of the present disclosure, and to methods of preparing the same.

Disclosed is a test soil comprising a plurality of molecules of labeled polypeptides, wherein the labeled polypeptide is a polypeptide to which a dye is added by a covalent bond, and the value of X calculated by the following formula is 100,000 or more:X=(Number of Dyes Comprised in One Molecule of Labeled Polypeptide)×(Molar absorption coefficient of dye (M−1 cm−1))

The present invention relates to a device that visually indicates the end of the useful life of a face protective device, in particular masks. Therefore, the present invention falls within the field of face masks against biological agents.

A medical instrument processor includes an enclosure, a liquid distribution system, and a disinfectant concentration measuring subsystem. The enclosure is configured to hold a medical instrument. The liquid distribution system is configured to deliver a disinfection solution to a medical instrument within the enclosure. The liquid distribution system has a liquid outlet. The disinfectant concentration measuring subsystem includes a first mixing chamber in fluid communication with the liquid outlet, a pump that is configured to simultaneously pump the disinfection solution and the reagent solution into the first mixing chamber, and a concentration analysis assembly that is operable to determine a concentration of disinfectant in a sample solution that is output from the first mixing chamber. The reservoir is in fluid communication with the first mixing chamber.

To provide a disinfectant visualization sheet that enables long-term storage, allows for easy visual checking of disinfectant application, and facilitates repeated use, and to provide disinfectant visualization particles.SOLUTION: A disinfectant visualization sheet includes: a substrate; and a coloring section that is disposed above the substrate. The coloring section includes a visualizing agent that shows a change in its coloring state upon application of a disinfectant. A coating section includes a silsesquioxane structure.SELECTED DRAWING: Figure 1

A sensor device. The sensor device includes a sterilant-responsive switch comprising: a circuit; a conductive polymer having a first state and a second state, and a polymeric binder; and wherein the sterilant-responsive switch connects the circuit in the first state and disconnects the circuit in the second state, and wherein the conductive polymer is capable of being converted from being in the first state to being in the second state when in contact with a sterilant.

A sterilization process challenge device for verifying the efficacy of a steam sterilization process includes first and second walls joined around their peripheries and a chamber defined therebetween for containing at least one sterilization indicator. The sterilization process challenge device also includes an inlet opening and a fluid flow path connected to the inlet opening to provide fluid communication between the inlet opening and the chamber. The fluid flow path is defined in a peripheral seal portion, wherein the only fluid communication between the chamber and an external environment is provided through the inlet opening and the fluid flow path.

A method of sterilisation, certification and traceability of liquid nitrogen, includes the steps of preparing a container, provided with an opening, in use, at the top, and pouring into it a batch of liquid nitrogen to be sterilised; providing an identification element uniquely associable with the batch of liquid nitrogen, said identification element including an indicator of the sterilisation state of the batch contained in said container configured to modify its appearance following exposure to ultraviolet radiation; associating the identification element with the container of the batch of liquid nitrogen to be sterilised, positioning it in a portion of said container, adjacent to said opening; carry out a batch sterilisation treatment through exposure to ultraviolet radiation for a predetermined period of time, to modify at least one characteristic of the indicator to certify the sterilisation of the batch.

Provided is a method and an apparatus for indicating minimum exposure of a surface to UVC light emitted by a source during a decontamination process to achieve a desired level of pathogen reduction. The apparatus includes a photochromic material to be applied to, or applied adjacent to the surface. The photochromic material is to exhibit a visible response to receiving the minimum exposure to the UVC light, and exhibit the visible response to a lesser extent after the photochromic material ceases to be exposed to the UVC light emitted by the source. A protective layer of material that is substantially transparent to the UVC light emitted by the source is positioned over the photochromic material to be disposed between the source and the photochromic material during the decontamination process.

An example sterilization indicator (102) includes a cover (122), an indicator (102), and a seal (142). The cover (122) defines at least a portion of a cavity (138). The indicator (102) is disposed within the cavity (138). The indicator (102) is configured to fluidly couple with an interior cavity (110) of a sterilization package (package) and indicate exposure to a sterilant. The seal (142) is configured to form a microbial barrier between an exterior of the cover (122) and the interior cavity (110) of the sterilization package (100).

The present disclosure provides embodiments of a sterilization indicator reading apparatus. The sterilization indicator reading apparatus includes a plurality of wells disposed in a housing configured to receive a plurality of biological indicators. Each well includes a first region spaced apart from a second region. A heater is thermally coupled with each well. The housing further includes a printed circuit board including a plurality of fluorescent excitation sources, plurality of white light sources, and plurality of color sensors. A first fluorescent excitation source, first white light source, and a first color sensor are disposed in the first region. A second white light source and a second color sensor are disposed in the second region. The printed circuit board further includes a processor and a memory. The processor is communicatively coupled with the heaters, the plurality of fluorescent excitation sources, plurality of white light sources, and plurality of color sensors.

This invention relates to a chemical indicator, comprising: a non-cellulosic backing layer; a non-cellulosic cover layer overlying the backing layer; the backing layer and / or the cover layer comprising a gas permeable polymeric film; a non-cellulosic wicking material positioned between the backing layer and the cover layer; a dye composition positioned between the backing layer and the cover layer and in contact with or nearly in contact with the wicking strip, the dye composition comprising an indicator dye which changes color in the presence of hydrogen peroxide, and a base medium, which melts at a temperature in the range from about 45°C to about 65°C; the cover layer including a transparent portion to permit observation of the wicking material; and an adhesive for adhering the cover layer to the backing layer. The chemical indicator may be referred to as a moving front chemical indicator. A process for conducting a vaporous hydrogen peroxide (VHP) sterilization process using the foregoing chemical indicator is disclosed.

A method of marking a residual aqueous contaminant on a surface 20 to be decontaminated comprises mixing a first part 11 of a marking system comprising a pH-sensitive dyestuff with first pH and first