The invention discloses ovine albumin-interferon τ-interleukin-2 fusion protein, a preparation method and its coding gene, a kind of ovine long-acting interferon, and ovine albumin, ovine interferon τ and ovine interleukin-2 are connected through a flexible linker , obtain ovine albumin-interferon τ-interleukin-2 fusion protein, design and optimize its coding gene, and finally prepare recombinant ovine long-acting interferon, which can significantly increase the half-life of ovine interferon, which is 17 times longer than that of ordinary ovine interferon Above, and has broad-spectrum antiviral effect and can improve the immune response of sheep itself.