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73results about How to "Has broad-spectrum antiviral effect" patented technology

Canine albumin-interferon alpha-interleukin 2 fusion protein, preparation method and coding gene thereof, and canine long-acting interferon

The invention discloses a canine albumin-interferon alpha-interleukin 2 fusion protein, a preparation method thereof and a coding gene thereof, and a canine long-acting interferon. Canine albumin, canine interferon alpha and canine interleukin 2 are connected by a flexible linker to obtain the canine albumin-interferon alpha-interleukin 2 fusion protein. The coding gene of the fusion protein is designed and optimized to finally obtain a recombinant canine long-acting interferon, which can significantly prolong the half-life of the canine interferon by more than 18 times in comparison with a common canine interferon, has a broad-spectrum antiviral effect and can improve the immune response of dogs.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD

Pig albumin-interferon alpha-interleukin 2 fusion protein as well as preparation method and encoding gene thereof, and long-acting interferon

The invention discloses pig albumin-interferon alpha-interleukin 2 fusion protein as well as a preparation method and an encoding gene thereof, and pig long-acting interferon. The pig albumin-interferon alpha-interleukin 2 fusion protein is obtained by connecting pig albumin, pig interferon alpha and pig interleukin 2 through a flexible linker, the encoding gene of the pig albumin-interferon alpha-interleukin 2 fusion protein is designed and optimized, and the recombinant pig long-acting interferon is finally prepared, so that the half-life period of the pig interferon can be prolonged obviously, the half-life period is prolonged by 27 times or above compared with that of the common pig interferon, the broad-spectrum antiviral action is achieved, and the autoimmune response of the pigs can be improved.
Owner:ANHUI JIUCHUAN BIOTECH

Fusion protein consisting of porcine albumin, porcine interferon gamma and porcine interferon alpha and preparation method of fusion protein

The invention discloses a fusion protein composed of porcine albumin, porcine interferon γ and porcine interferon α and a preparation method thereof. The fusion protein is composed of porcine albumin, porcine interferon γ and porcine interferon α through a flexible linker The recombinant porcine peginterferon can be obtained after the fusion protein is mixed with a freeze-drying protective agent and freeze-dried. The recombinant porcine long-acting interferon can significantly increase the half-life of porcine interferon, which is more than 24 times higher than that of ordinary porcine interferon, has broad-spectrum antiviral effect and can improve the immune response of pigs themselves.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD

Fusion protein composed of chicken albumin, chicken interferon gamma and chicken interferon alpha and preparation method thereof

The invention discloses a fusion protein composed of chicken albumin, chicken interferon gamma and chicken interferon alpha and a preparation method thereof. The fusion protein is composed of chicken albumin, chicken interferon gamma and chicken interferon alpha through a flexible linker The recombinant chicken peginterferon can be obtained after the fusion protein is mixed with the freeze-drying protective agent and freeze-dried. The recombinant chicken long-acting interferon can significantly increase the half-life of chicken interferon, which is more than 22 times higher than that of common chicken interferon, has broad-spectrum antiviral effect and can improve the immune response of chicken itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD

Fused protein composed of sheep interleukin 2, sheep interferon gamma and sheep interferon tau and preparation method of fused protein

The invention discloses a fusion protein composed of goat interleukin 2, goat interferon gamma and goat interferon tau and a preparation method thereof. The fusion protein is composed of goat interleukin 2, goat interferon gamma and goat interferon τ is formed by connecting with a flexible linker, the fusion protein is mixed with a freeze-drying protective agent, and then freeze-dried to obtain recombinant sheep peginterferon. The recombinant sheep long-acting interferon can significantly increase the half-life of sheep interferon, which is more than 15 times higher than that of ordinary sheep interferon, has broad-spectrum antiviral effect and can improve the immune response of sheep itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
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