Method for carrying out high efficiency premixing reaction
A pre-mixing and reaction technology, applied in chemical instruments and methods, preparation of lactam, organic chemistry, etc., can solve the problems of many by-products, low single-pass conversion rate, long residence time and other problems of amidation reaction, and achieve material retention small size, high mass transfer efficiency, and short residence time
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Embodiment 1
[0017] Use the stainless steel plate film that aperture is 1 μ m as dispersion medium, take 5% cyclohexane carboxylic acid n-hexane solution and oleum as reaction material, the volume flow ratio of cyclohexane carboxylic acid n-hexane solution and oleum is 100: 1. After the two phases are mixed, the flow velocity along the surface of the dispersion medium is 0.1m / s, and the reaction time is 0.1s. Measure the concentration of cyclohexane carboxylic acid remaining in the n-hexane solution after the reaction, and obtain it based on cyclohexane carboxylic acid The conversion rate of the reaction is 51.2%.
Embodiment 2
[0019] Use a glass flat membrane with a pore size of 0.2 μm as the dispersion medium, take 10% n-hexane carboxylic acid solution and oleum as the reaction materials, and the volume flow ratio of the n-hexane carboxylic acid solution and oleum is 50 : 1, after the two phases are mixed, the flow velocity along the surface of the dispersion medium is 1m / s, and the reaction time is 0.01s. After measuring the remaining cyclohexanecarboxylic acid concentration in the n-hexane solution after the reaction, it is determined that the cyclohexanecarboxylic acid is used as a benchmark The reaction conversion rate is 83.3%.
Embodiment 3
[0021] A stainless steel tubular membrane with a pore size of 5 μm is used as the dispersion medium, and 10% n-hexane solution of cyclohexanecarboxylate and oleum are used as reaction materials, and the volume flow ratio of n-hexane solution of cyclohexanecarboxylate and fuming sulfuric acid is 5 : 1, after the two phases are mixed, the flow velocity along the surface of the dispersion medium is 2m / s, and the reaction time is 0.01s. After measuring the remaining cyclohexanecarboxylic acid concentration in the n-hexane solution after the reaction, it is determined that the cyclohexanecarboxylic acid is used as a benchmark The reaction conversion rate is 93.6%.
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