Kangai drip pill for treating tumour, hepatitis B and its preparation method
A technology for Kangai dropping pills and tumors, which can be used in anti-tumor drugs, medical preparations containing active ingredients, and pill delivery. Gastrointestinal irritation symptoms, improved bioavailability, dissolution and absorption acceleration
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[0031] Now with several groups of specific examples, the preparation method of the Kangai dripping pills of the present invention will be further described.
[0032] [Group 1: Trials with a single substrate]
[0033] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of traditional Chinese medicine astragalus, ginseng and matrine is pre-prepared for use;
[0034] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;
[0035] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;
[0036] 4. Prepare according to the process given in [Preparation Method] 4-7 to obtain Kangai Dropping Pills of different specifications.
[0037] [test results]
[0038] Experiment 1: In order to observe the diff...
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