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Suppository for treating chronic cervicitis

A technology of chronic cervicitis and suppositories, which is applied in the field of drugs for the treatment of chronic cervicitis, and can solve problems such as cervical stenosis, infection, and long healing time

Inactive Publication Date: 2008-11-19
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, various physical treatments are often used clinically, such as freezing, electric ironing, laser, infrared rays, etc., to destroy the columnar epithelium on the erosive surface of the cervix, make it necrotic and fall off, and be covered by new squamous epithelium, but there are postoperative bleeding and infection. , long healing time, the possibility of infertility caused by cervical stenosis, and many adverse reactions to vaginal delivery, and it also brings a lot of inconvenience to patients' daily life

Method used

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  • Suppository for treating chronic cervicitis
  • Suppository for treating chronic cervicitis
  • Suppository for treating chronic cervicitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0092] Embodiments of the present invention will be described below, but the content of the present invention is not limited thereto at all.

[0093] KGF-2

glycerin gelatin

stabilizer

buffer

Protective agent

Example 1

0.02％

90％

Sucrose 6%

Phosphate 3.48%

Human albumin 0.5%

Example 2

0.04％

92％

Glucose 2.16%

Citrate 4%

Bovine serum albumin 1.8%

Example 3

0.08％

88％

Trehalose 8%

Acetate 3.07%

Human Albumin 0.85%

Example 4

0.10％

94％

Glucose 3%

Citric acid 2.36%

Human Albumin 0.54%

Example 5

0.30％

91％

Lactose 7%

Glutaric acid 1.14%

Human albumin 0.56%

Example 6

0.90％

91％

Mannitol 4.18%

Citric acid 2.1%

Human Albumin 1.82%

Example 7

1.3％

86％

Mannitol 7.79%

Aconitic acid 3.71%

Bovine serum albumin 1.2%

Example 8

1.5％

90％

La...

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PUM

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Abstract

A medicine in the form of suppository for treating chronic cervicitis is prepared from horny cell growth factor-2, matrix, stabilizer, buffering agent and protecting agent.

Description

technical field [0001] The present invention relates to a kind of medicine for treating chronic cervicitis, more specifically relate to a kind of suppository for treating chronic cervicitis, this suppository is a kind of vaginal suppository containing keratinocyte growth factor-2 (Keratinocyte growth factor-2, KGF-2) . Background technique [0002] Keratinocyte growth factor-2 (Keratinocyte growth factor-2, KGF-2), also known as fibroblast growth factor-10 (fibroblast growth factor-10, FGF-10), is a member of the FGF family. It is secreted by fibroblasts and other mesenchymal cells, and its specific target cells are various epithelial cells. is a cytokine that regulates the mesenchymal-epithelial interaction. KGF-2 specifically promotes the proliferation, differentiation and migration of epithelial cells, and is an important multifunctional signaling molecule in the development of embryonic organs. It can stimulate the regeneration, differentiation and migration of epithe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/18A61K9/02A61K47/42A61P15/00A61P15/02
Inventor 杨静尹龙武李颖敖英彭仁琇夏雪雁孔锐
Owner WUHAN UNIV
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