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Chinese medicine preparation for treating stroke

A technology of traditional Chinese medicine preparations and medicinal materials, which is applied in the direction of medical preparations containing active ingredients, pill delivery, drug combination, etc., can solve the problem of ineffective treatment of stroke, achieve strong stability and specificity, and high medicinal safety , the effect of low production cost

Active Publication Date: 2009-07-22
TONGYAO PHARMA GROUP CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many modern Chinese patent medicines related to the treatment of stroke. Traditional patent medicines (pills), such as "Da Huo Luo Dan", "Ginseng Zaizao Pills", etc., recently appeared "Huatuo Zaizao Pills" and "Xiaoshuan Zaizao Pills". etc., as well as related emergency medicines for cardiovascular and cerebrovascular diseases, such as "Guanxinsuhe Pills" and "Angong Niuhuang Pills", etc. are flooding the market. These medicines have no significant therapeutic effect on stroke.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Take Gastrodia elata 282 grams, Uncaria 705 grams, Scutellaria baicalensis 282 grams, Panax notoginseng 141 grams,

[0042] 282 grams of Shouwu, 564 grams of Radix Paeoniae Alba, 470 grams of Achyranthes bidentata, 564 grams of Sangjisi,

[0043] Cuscuta 705g, Alisma 282g, Cassia 470g, Guangdilong 470g for later use;

[0044] The preparation method is as follows:

[0045]Rinse the above 12 traditional Chinese medicines with clean water, and decoct the remaining 11 herbs except Uncaria twice with water. For the first decoction, add 10 times the amount of medicinal materials, decoct for 90 minutes, and filter; add water for the second decoction, add 8 times the amount of medicinal materials, decoct for 60 minutes, and filter; combine the two filtrates Concentrate into a thick paste in a vacuum concentration tank, dry, pulverize, and pass through a 80-mesh sieve. Another rinsed Uncaria vine was extracted twice with 70% ethanol under reduced pressure, 1.5 hours each time...

Embodiment 2

[0047] Take Gastrodia elata 300 grams, Uncaria 650 grams, Scutellaria baicalensis 260 grams, Panax notoginseng 180 grams,

[0048] 310 grams of Radix Polygoni Multiflori, 550 grams of Radix Paeoniae Alba, 520 grams of Achyranthes bidentata, 570 grams of Sangjisi,

[0049] Cuscuta 680g, Alisma 250g, Cassia 500g, Guangdilong 500g for later use;

[0050] The preparation method is the same as in Example 1.

Embodiment 3

[0052] Take the standby dry paste powder of the raw medicinal materials or their extracts prepared by the method in Example 1, add 1 / 3 of the amount of dextrin to the dry paste powder, then add an appropriate amount of stevioside, stir evenly, and use an appropriate amount of 80% ethanol to make granules Granules 1000g, dried, granulated, and packed separately. Each bag of this product contains baicalin (C 21 h 18 o 11 ) shall not be less than 8mg, gastrodin (C 13 h 18 o 7 ) shall not be less than 0.282mg. [Specification] 8g / bag.

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PUM

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Abstract

A traditional Chinese medicine preparation for treating apoplexy belongs to the technical field of traditional Chinese medicines, and specifically relates to a traditional Chinese medicine preparation for treating apoplexy caused by liver and kidney yin deficiency, disturbance of wind and yang, and cerebral stasis. The invention also provides a preparation method and application of the traditional Chinese medicine preparation. The present invention is mainly made from Gastrodia elata, Uncaria baicalensis, Scutellaria baicalensis, Panax notoginseng, Zhishouwu, Radix Paeoniae Alba, Achyranthes bidentata, Semen mulberry, Cuscuta chinensis, Alisma, Semen Cassiae, and Cangdilong raw materials; it is prepared by the following method: Wash the above 12 flavors, add water to decoct the other 11 flavors except Uncaria twice, combine the filtrate, concentrate under reduced pressure to form a thick paste, dry, pulverize, and sieve; Uncaria is extracted twice with ethanol under reduced pressure and reflux, and concentrated into After thickening the paste, dry it at low temperature; pulverize, sieve, and combine the dry paste powder to make granules, or pills, or capsules, or soft capsules, or tablets, or mixtures. The preparation process of the invention is simple, the production cost is low, the loss of active ingredients is small, the yield is high, the process route is stable, the large-scale production is easy, and the clinical effect is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for treating apoplexy caused by liver and kidney yin deficiency, disturbance of wind and yang, and cerebral vein stasis. The invention also provides a preparation method and application of the traditional Chinese medicine preparation. Background technique [0002] Stroke, also known as "stroke", is characterized clinically by "sudden coma, unconsciousness, crooked mouth and eyes, strong tongue, hemiplegia, and insensitive skin". According to the statistics of the World Health Organization, among the top ten killers of human health in the 20th century, stroke ranked second, and the number of people who died of stroke in the world was as high as 5.1 million every year. Its morbidity rate is high, and most of the surviving patients are left with different degrees of disabilities, especially hemiplegia, aph...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61K36/74A61K36/539A61K36/258A61K9/16A61K9/20A61K9/48A61P9/10
Inventor 陆志正高陆张彦彦康亚娟白海平石光高红梅周雪凡鞠凤霞郭庆伟
Owner TONGYAO PHARMA GROUP CORP
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