Aidi drops for treating cancers and preparation thereof

A technology of Aidi dropping pills and lung cancer, which is applied in the field of Aidi dropping pills for the treatment of cancer and its preparation, can solve the problems of long dissolution time, heavy financial burden on patients, low dissolution rate, etc., and avoid gastrointestinal irritation symptoms , Improve bioavailability, accelerate dissolution and absorption

Inactive Publication Date: 2009-08-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Due to the limitation of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions, and there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy financial burden for patients, unsuitable for family use and other disadvantages
[0013] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the drug efficacy. The play also directly affects the therapeutic effect
At the same time, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0039] Now with several groups of specific examples, the preparation method of Aidi dropping pills of the present invention will be further described.

[0040] Group 1: Tests with a single matrix

[0041] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then follow the section [Appendix: A Preparation Method of a Chinese Medicine Extract] to first prepare the active ingredients containing Chinese medicine Mylabris, Ginseng, Astragalus, and Acanthopanax. The extract dry powder of the ingredients is ready for use;

[0042] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0043] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:9;

[0044] 4. Then prepare acco...

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PUM

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Abstract

An Aidi dripping pill based on Aidi injection for treating primary liver cancer, lung cancer, rectum cancer, lymph cancer and gynopathic malignant tumor is disclosed. Its advantages are high release speed and quickly taking its high effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition with the functions of clearing away heat and detoxifying, eliminating blood stasis and dissipating stagnation, and is used for treating primary liver cancer, lung cancer, rectal cancer, malignant lymphoma, gynecological malignant tumor and other diseases, especially Aidi which is formulated with traditional Chinese medicine Based on the prescription of injection, it is an oral preparation reformed from the dosage form. Background technique [0002] (Ministry 20-85) [0003] According to the drug standard WS issued by the national ministry 3 -Aidi Injection, prepared according to the formula and extraction process given in B-3809-98, is a pure injection used for the treatment of primary liver cancer, lung cancer, rectal cancer, malignant lymphoma, gynecological malignant tumors and other diseases. Traditional Chinese medicine injections have been clinically verified for many years, with stable qual...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K36/481A61K36/258A61K36/254A61K35/64A61P35/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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