Chinese medicine red sage-astragalus root preparation for treating liver fibrosis and liver cirrhosis and its preparation process
A traditional Chinese medicine preparation, liver fibrosis technology, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, pill delivery, etc., can solve the problems of low content of active pharmaceutical ingredients, complicated production process, poor patient compliance, etc., and achieve significant curative effect. , The effect of advanced production technology and many active ingredients
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Embodiment 1
[0048] The components of the medicine for treating liver fibrosis and liver cirrhosis in this example and their weight proportions are: 75 parts of total astragalus polysaccharides, 10 parts of total astragalus saponins, 10.5 parts of total phenolic acids of salvia miltiorrhiza, and 4.5 parts of total tanshinones. Its dosage form is capsule. It can be prepared by the following steps:
[0049] (1) Extract astragalus polysaccharide and astragalus saponin from Astragalus
[0050] a. Water extraction: Take the astragalus cut into pieces, add water and decoct 3 times, 2 hours each time, filter, combine the filtrate, concentrate to 3 times the amount of crude drug, centrifuge at high speed, and concentrate the centrifugate to relative density under reduced pressure 1.1;
[0051] b. Alcohol precipitation: add ethanol to make the alcohol content reach 60%, let it stand for 24 hours, filter, and recover the ethanol from the filtrate until it has no alcohol smell, and obtain the filtr...
Embodiment 2
[0061] The components of the medicine for treating liver fibrosis and liver cirrhosis in this example and their weight percentages are: 50 parts of total astragalus polysaccharides, 3 parts of total astragalus saponins, 20 parts of total phenolic acids of salvia miltiorrhiza, and 10 parts of total tanshinone. Its dosage form is a tablet. It can be prepared by the following steps:
[0062] (1) Extract astragalus polysaccharide and astragalus saponin from Astragalus
[0063] a. Water extraction: take the astragalus cut into pieces, add water and decoct 3 times, 1 hour each time, filter, combine the filtrate, concentrate to 1.5 times the amount of crude drug, centrifuge at high speed, and concentrate the centrifugate to relative density under reduced pressure 1.1;
[0064] b. Alcohol precipitation: Add ethanol to make the alcohol content reach 50%, let it stand for 20 hours, filter, and recover the ethanol from the filtrate until it has no alcohol smell, and obtain the filtrate...
Embodiment 3
[0074]The components of the medicine for treating liver fibrosis and liver cirrhosis in this example and their weight percentages are: 80 parts of total astragalus polysaccharides, 20 parts of total astragalus saponins, 5 parts of total phenolic acids of salvia miltiorrhiza, and 2 parts of total tanshinone. Its dosage form is granules. It can be prepared by the following steps:
[0075] (1) Extract astragalus polysaccharide and astragalus saponin from Astragalus
[0076] a. Water extraction: Take the astragalus cut into pieces, add water and decoct 3 times, 3 hours each time, filter, combine the filtrate, concentrate to 4 times the amount of crude drug, centrifuge at high speed, and concentrate the centrifugate to relative density under reduced pressure 1.4;
[0077] b. Alcohol precipitation: Add ethanol to make the alcohol content reach 70%, let it stand for 28 hours, filter, and recover the ethanol from the filtrate until it has no alcohol smell, and obtain the filtrate of...
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