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Medicine for treating nonunion and method for preparing the same

A nonunion and drug technology, used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of severe patient pain, slow functional recovery, poor effect, etc., and achieve excellent clinical effects and increase The effect of bone density

Inactive Publication Date: 2008-01-30
陈树亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Excision of the hardened end, opening up the occluded medullary cavity, and strong internal fixation are the basic principles of Western medicine in the treatment of nonunion. This treatment method is based on surgical treatment. The patient suffers from great pain, slow functional recovery, high cost, and poor effect, so it cannot be treated. Some nonunions that cannot be treated with internal fixation surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0009] Specific embodiment 1: A kind of medicine for the treatment of nonunion is composed according to weight ratio: 10 kilograms of Cordyceps sinensis, 20 kilograms of antler, 10 kilograms of Sichuan section, 10 kilograms of Chuanshanlong, 10 kilograms of raw licorice, 10 kilograms of tortoise shell, broken stomach Supplement 10 kg, Sangji 10 kg, Angelica 15 kg, Rhubarb 10 kg, Bletilla striata 2025 kg, Blood dried fruit 5 kg, Musk (introduction) 1 kg, Bezoar 1 kg, Ephedra 3 kg, Safflower 20 kg, Semen chinensis 8 kg, 1 kg of Chuanwu, 1 kg of Aconitum.

[0010] Among the medicines, Cordyceps, pilose antler, tortoise shell, dried blood, musk, and bezoar are ground into 200 mesh sieves for later use, and Rhizoma Drynariae, Psoralen, Sangji, Chuanshanlong, raw licorice, Bletilla striata, ephedra, rhubarb, Concentrated extraction of angelica, horseshoe, aconitum, and aconitum, put the spare medicine in, stir evenly, and then make granules, tablets, granules, honey pills, capsules,...

specific Embodiment 2

[0011] Specific embodiment 2: a kind of medicine for treating nonunion is composed according to weight ratio: 11 kilograms of Cordyceps sinensis, 25 kilograms of antler, 15 kilograms of Chuanduan, 15 kilograms of Chuanshanlong, 11 kilograms of raw licorice, 15 kilograms of tortoise shell, bone fragments 11kg tonic, 14kg mulberry, 30kg angelica, 11kg rhubarb, 25kg bletilla striata, 10kg blood jellyfish, 3kg musk (introduction), 3kg bezoar, 6kg ephedra, 25kg safflower, zhimaqianzi 7 kg, Aconitum 3 kg, and Aconitum 3 kg.

[0012] Among the medicines, Cordyceps, pilose antler, tortoise shell, dried blood, musk, and bezoar are ground into 200 mesh sieves for later use, and Rhizoma Drynariae, Psoralen, Sangji, Chuanshanlong, raw licorice, Bletilla striata, ephedra, rhubarb, Concentrated extraction of angelica, horseshoe, aconitum, and aconitum, put the spare medicine in, stir evenly, and then make granules, tablets, granules, honey pills, capsules, and water pills. The dosage is 0....

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PUM

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Abstract

The present invention relates to a drug for treating bone nonunion and the preparation method, the components of which are: 10 to 11kg of Chinese caterpillar fungus, 20 to 25kg of hairy antler, 10 to 15kg of himalayan teasel root, 10 to 15kg of Ningpo yam rhizome, 10 to 11kg of liquoric root, 10 to 15kg of turtle shell, 10 to 11kg of drynaria rhizome of fortune, 10 to 14kg of Chinese taxillus twig, 15 to 30kg of Chinese angelica, 10 to 11kg of rhubarb, 20 to 25kg of bletilla striata, 5 to 10kg of Sanguis Draconis, 1 to 3kg of musk (an added ingredient to enhance the efficacy of the medicines), 1 to 3kg of bezoar, 3 to 6kg of ephedra herb, 20 to 25kg of safflower, 7 to 8kg of prepared nux vomica, 1 to 3kg of common monkshood mother root and 1 to 3kg of kusnezoff monkshood root. Among the medicines, the Chinese caterpillar fungus, hairy antler, turtle shell, Sanguis Draconis, musk and the bezoar are ground into the fine powder which can pass through the 200 mesh screen for ready use, other medicines are concentrated and extracted, the medicines for ready use are added for even agitating, so as to be prepared into the granules, tablets, granules, honey pills, capsules and water pills. The dosage is 0.01 to 0.03g per kg of the body weight and 3 to 4 times per day for oral administration. The prescription composition can effectively treat the bone nonunion with less suffering of the patients, fast function recovery and low cost.

Description

Background technique [0001] Not every fracture patient’s fracture can heal as scheduled. Those who have not achieved clinical healing within 4 months are regarded as slow union, and those who do not heal after 8 months are considered nonunion. In practice, if the fracture has not healed after 6 months , some doctors treat it as nonunion. Nonunion occurs in about 5% of fracture patients, and nonunion often occurs in femoral neck fractures, tibia middle and lower 1 / 3 fractures, humeral shaft fractures, and femoral fractures. Currently, many fractures are treated with external fixators, plates, and intramedullary nails. The advantage of these treatments is better positioning, the disadvantage is the increased incidence of nonunion. Taking the humerus as an example, the nonunion incidence rate of fractures treated with plaster is only 2-5%, but the incidence rate of nonunion treatment with open surgery and internal fixation is as high as 25-30%. [0002] There are many ways to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/16A61K9/20A61K9/48A61P19/08A61K35/56A61K35/32A61K35/413A61K35/55A61K35/586
Inventor 陈树亮陈柏炫
Owner 陈树亮