Pharmaceutical composition

A composition and drug technology, applied in the direction of drug combination, active ingredient of iodine compound, antibacterial drug, etc., can solve the problem of affecting the effect of insecticidal, unable to play the role of sterilization, etc., and achieve stable molecular structure and long-lasting effect. effect of sex

Inactive Publication Date: 2008-05-21
王德昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Amprolium is a parasitic drug with good curative effect, but its current use is mainly limited to anticoccidia, and it cannot play a sterilizing role when bacterial infections are incidental to some diseases, and sometimes even Affect the effect of insecticide

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Take 1Kg of amproline, dissolve it with 10Kg of water, add it to 900Kg of 1% povidone iodine solution, then add 89Kg of water, heat to 30°C, stir and mix for 30min to make a stable and transparent liquid, keep it for 1h, and pack it out to get the finished product.

Embodiment 2

[0022] Take 5Kg of amprolium hydrochloride, dissolve it in 50Kg of water, add it to 700Kg of 1% complex iodine solution, then add 245Kg of water, heat to 30°C, stir and mix for 30min to make a stable transparent liquid, keep it for 1h, The finished product is obtained from the output packaging.

Embodiment 3

[0024] Take 10Kg of amprolium tartrate, dissolve it with 100Kg of water, add it to 500Kg of 1% compound iodine solution, then add 390Kg of water, stir and mix at 30°C for 30min to make a stable and transparent liquid, keep it for 1h, and pack it out to get finished product.

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PUM

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Abstract

The invention relates to a pharmaceutical composition, which contains 0.1 to 10 percent amprolium or salt for pharmaceutical use and 0.1 to 5 percent effective iodine and is matched with other additives for preparation. The pharmaceutical composition of the invention makes up the shortcoming that the drugs for the prevention and treatment of various aquatic products on the current market have the single efficacy; at the same time, the invention has the effects of sterilization, disinfection and killing parasites, and has good efficacy on gill rot, hemorrhage and various diseases caused by parasites, bacteria and virus of various fishes, shrimps, crabs, soft-shelled turtles, eels and so on; the invention has good killing function of trichodina, dactylogyrus and other parasites, can also be used in the mixed cultivation pond of fishes, shrimps, crabs and so on, and has significant efficacy which is proved by clinical application.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition with amproline and iodine as active ingredients, and the pharmaceutical composition is mainly used in the field of aquatic biological prevention and control. Background technique [0002] Amprolium, also known as amprolium, is a white, odorless acidic powder, easily soluble in water, methanol and ethanol, slightly soluble in ether, and insoluble in chloroform. Amprolium has a similar chemical structure to thiamine and can competitively inhibit the uptake of thiamine by coccidia. In coccidian cells, thiamine is synthesized into thiamine pyrophosphate, which participates in the oxidative decarboxylation of α-ketoacids in the process of sugar metabolism, and is a coenzyme in the α-ketoacid dehydrogenase system. Because amprolium lacks the hydroxyethyl group of thiamine, it cannot be pyrophosphorylated, so many reactions cannot be carried out, hindering th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/18A01N59/12A01P1/00A01P3/00A61P33/14A61P31/04A61P31/12A61K31/506
Inventor 王德昌
Owner 王德昌
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