Controllable minimal invasive injection unit applied on thermochemical targeting ablation therapeutic for tumour

An injection device and thermochemical technology, applied in the field of medical devices, can solve the problems of dependence on surgical treatment effects, etc., and achieve the effects of easy access to the human body, reliable driving process and surgical process, and cost reduction

Inactive Publication Date: 2008-06-25
TSINGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This has resulted in the disadvantage that the effect of surgical treatment is heavily dependent on the experience and medical skills of doctors.

Method used

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  • Controllable minimal invasive injection unit applied on thermochemical targeting ablation therapeutic for tumour
  • Controllable minimal invasive injection unit applied on thermochemical targeting ablation therapeutic for tumour
  • Controllable minimal invasive injection unit applied on thermochemical targeting ablation therapeutic for tumour

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] As shown in FIG. 1 , this embodiment has the function of injecting chemical substances in a single channel, and is used in conventional chemical ablation operations. The package includes: control and display device 1, stepping motor 2, degassing tube 3, acid and alkali resistant hose 4, peristaltic pump 5, reagent bottle 6, injection microneedle 7, sponge plug 8, glass tube packaged thermocouple or pH sensor 11.

[0027] During the operation, the operator controls the flow rate of the output liquid through the keyboard digital input in the control and display device 1, and manually controls the operation process through the start and stop buttons, and can input the target flow rate of the peristaltic pump in real time. The display module of the control and display device 1 can display the current flow rate and the physiological parameters (temperature or pH value) at the position of the sensor. The upper limit value of the physiological parameter is preset in the single...

Embodiment 2

[0029] As shown in Figure 4, the device contains a multi-injection system (only 2-way tubing is shown in the figure). It consists of a control and display device 1, one or more glass tube-encapsulated thermocouples or pH sensors 11, and two or more injection systems, each of which includes a stepping motor 2, a peristaltic pump 5, and a reagent bottle 6. Acid and alkali-resistant hose 4 and injection microneedle 7; the control and display device 1 consists of a single-chip microcomputer, a multi-channel A / D converter, a multi-channel D / A converter, a display device, a keyboard, a power supply module and sensor signals The acquisition and processing module is composed of; the single-chip microcomputer is connected with the stepping motor and the sensor signal acquisition and processing module through D / A and A / D converters respectively; the sensor signal acquisition and processing module is connected with the thermocouple packaged in glass tube Or the pH sensor 11 is electrical...

Embodiment 3

[0033] Fig. 5 is a schematic diagram of the branch injection system of the present invention; Fig. 6 is a partially enlarged view of the branch injection system of the present invention. In this device, the injection system adopts a branch injection system, and the reagent bottle 6 adopts two or more, and each reagent bottle is connected to the three-way or multi-way connecting pipe 10 through the acid and alkali resistant rubber hose of each branch, and then It is connected with the injection microneedle 7 through the total acid and alkali resistant rubber tube.

[0034] In this embodiment, on the basis of Embodiment 1, a music cock 9 and a three-way or multi-way connecting pipe 10 are added. The output ends of two or more rubber hoses driven by the peristaltic pump are merged to the total acid and alkali resistant rubber hose through the three-way or multi-way connecting tube 10, and then injected into the target tissue in the human body through the connected injection micro...

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Abstract

The utility model relates to a controllable minimal invasive injection device used in tumor thermochemistry target ablation therapy, which pertains to medical apparatus and instruments technical field. The device consists of a control and display device, a glass tube encapsulated thermocouple or a pH sensor and a channel or multiple channels of injection system. Each channel of injection system comprises a stepping motor, a peristaltic pump, a reagent bottle, an acid and alkali-resistant hose and an injection micropipette. The invention can inject drugs, especially acid and alkali chemical ablation solution to a tumor part, employ the peristaltic pump as a power conversion device to apply to tumor chemical ablation therapy, and utilize extremely slow exit velocity to improve controllability and safety of operation; the device can be improved to a plurality of devices for different operation models, providing a workable device for tumor thermochemistry ablation therapy. In addition, the device employs the thermocouple or pH sensor to detect physiological status of target tissues, and feed back the status to a control system through a circuit, thus leading an ablation operation to realize a certain degree of quantification.

Description

technical field [0001] The invention relates to a precise and controllable injection device for tumor thermochemical targeted ablation therapy, which can inject drugs, especially acid and alkali chemical ablation solutions, into the tumor site to be treated, and perform conventional chemical ablation; it belongs to medical device technology field. Background technique [0002] In the treatment of malignant tumors, surgical resection, radiotherapy and chemotherapy have long been recognized as the most standard treatments. However, surgical resection is very destructive and causes limb deformities, and the side effects caused by radiotherapy and chemotherapy often bring serious physical and mental pain to patients. All these factors will inevitably reduce the survival rate and quality of life of patients. Therefore, seeking a minimally invasive treatment that can effectively kill tumor cells and ensure less damage and side effects has always been a major goal pursued by the c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/00A61B18/00
Inventor 黄昱董莹徐迪刘冉刘静
Owner TSINGHUA UNIV
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