Heat-clearing and detoxication antiphlogistic detumescence Chinese medicinal composition and preparation thereof

A heat-clearing, detoxifying, and composition technology, applied in the field of traditional Chinese medicine composition and its preparation, can solve problems affecting drug quality monitoring, lack of content determination standards, poor acceptance by patients, etc., and achieve controllable drug quality and reduce transportation and storage The effect of stable cost and curative effect

Inactive Publication Date: 2008-07-02
TIANJIN ZHONGXIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The dosage of each dose of this variety is too large, children, the elderly and patients with pharyngitis have difficulty swallowing, it is inconvenient to take, and the patient's acceptance is poor
And in terms of quality control, there is still a lack of content determination standards, and it is not easy to control quality
This will not only directly affect the curative effect of new drugs, but also affect the quality control of drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Scutellaria baicalensis 2400g Dandelion 6400g

[0036] Kudiding 1600g Banlangen 1600g

[0037] a. Take each raw material according to the ratio of raw materials, and set aside;

[0038] b. Scutellaria baicalensis was extracted twice with 10 times and 8 times the amount of hot water respectively, the first extraction was 1.5 hours, and the second extraction was 1 hour. The aqueous extract was adjusted to a pH value of 1 with 2mol / L hydrochloric acid, allowed to stand, and filtered to obtain a precipitate, which was dried to obtain a dried product I;

[0039] c. Dandelion, kudiding, and Radix Radix were extracted twice with 10 times and 8 times of water respectively. The first extraction was 1.5 hours, and the second extraction was 1 hour. Combine the extracts, concentrate them into a thick paste, and add 95% ethanol Adjust the alcohol content of the solution to 50%, carry out alcohol precipitation, and obtain the supernatant B;

[0040] d. Concentrate the supernatant ...

Embodiment 2

[0046] Skullcap 135g Dandelion 360g

[0047] Kudiding 90g Radix Radix 135g

[0048] a. Take each raw material according to the ratio of raw materials, and set aside;

[0049] b. Scutellaria baicalensis was extracted twice with 8 times and 6 times the amount of hot water respectively, the first extraction was 1.5 hours, and the second extraction was 1.5 hours. The aqueous extract was adjusted to a pH value of 2 with 1mol / L hydrochloric acid, left to stand, and filtered to obtain a precipitate, which was dried to obtain a dry product I;

[0050] c. Dandelion, kudiding, and Radix Radix were extracted twice with 6 times and 4 times of water respectively, the first extraction was 1.5 hours, the second extraction was 1 hour, the extracts were combined, concentrated into a thick paste, and 95% ethanol was added Adjust the alcohol content of the solution to 80%, carry out alcohol precipitation, and obtain the supernatant B;

[0051] d. Concentrate the supernatant A into a thick paste...

Embodiment 3

[0054] Scutellaria baicalensis 90g Dandelion 240g

[0055] Kudiding 60g Radix Radix 90g

[0056] a. Take each raw material according to the ratio of raw materials, and set aside;

[0057] b. Scutellaria baicalensis was extracted twice with 6 times and 4 times the amount of hot water respectively, the first extraction was 2 hours, and the second extraction was 1.5 hours. The aqueous extract was adjusted to a pH value of 2 with 2 mol / L hydrochloric acid, left to stand, filtered to obtain a precipitate, which was dried to obtain a dried product I;

[0058] c. Dandelion, kudiding, and Radix Radix were extracted twice with 7 times and 5 times of water respectively. The first extraction was 1.5 hours, and the second extraction was 1.5 hours. Combine the extracts, concentrate them into a thick paste, and add 95% ethanol Adjust the alcohol content of the solution to 75%, carry out alcohol precipitation, and obtain supernatant B;

[0059] d. Concentrate the supernatant A into a thic...

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PUM

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Abstract

The invention aims at providing a Chinese traditional medicine combination used for clearing away heat and toxic material, diminishing inflammation and reducing edema and a preparation method thereof; the Chinese medicine combination consists of the following raw medicines by weight proportion: 3 portions of radix scutellariae, 8 portions of dandelion, 2 portions of bunge corydalis herb and 3 portions of radix isatidis. The preparation steps are as follows: a. every raw material is weighed and taken according to the above proportion ready for use; b. radix scutellariae is extracted by water, the water extract is adjusted to acidity, standing still to obtain sediment, and then the sediment is dried so as to obtain dried material I; c. radix isatidis, dandelion and bunge corydalis herb are extracted by water, and then the water extracts are merged, concentrated into thick paste, added with ethanol for alcohol precipitation so as to obtain supernatant fluid A; d. the supernatant fluid A is concentrated into thick paste which is dried to obtain dried material II; e. the dried material I and the dried material II are mixed so as to obtain the active ingredients of the medicine of the invention; the Chinese medicine combination has reasonable dosage, and is convenient for oral administration and carrying; the technique of the preparation method is reasonable and stable, and can prepare the medicine that has controllable quality and can fully achieve curative effect. The invention is suitable for industrial production.

Description

(1) Technical field: [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for clearing away heat, detoxification, anti-inflammation and detumescence and a preparation method thereof. (two) background technology: [0002] Cold is an extremely common disease. Modern studies have shown that more than 90% of the common cold is caused by viruses, especially people with particularly weak resistance (the elderly and infirm, infants and young children, and people who are sick) are particularly susceptible. Cold viruses infect the upper respiratory tract, causing swelling and inflammation of the mucous membranes of the sinuses, pharynx, and larynx, causing symptoms such as sore throat, cough, and fever. [0003] Nowadays, fried, barbecued fast food, snack food, and spicy dishes such as Sichuan cuisine and Cantonese cuisine are becoming more and more popular in people's ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61K47/02A61K47/12A61K47/16A61K47/22A61K47/26A61K47/36A61K47/38A61K47/40A61P29/00A61P31/00A61P11/00A61P11/04
Inventor 潘勤王欣蓝苑元耿彤曲乐毅薛宁
Owner TIANJIN ZHONGXIN PHARMA GRP CO LTD
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