Method for extracting crude flavone and flavone glycoside from ginkgo leafs

Abstract

The invention provides a method for extracting crude flavonoids and glycoside from ginkgo leaves, which relates to an extracting method of drug, in particular to an extracting and purifying method of effective components of Chinese medicine. Flocculating clarification method is used for treating water extract of ginkgo leaves; then purification is carried out before alcohol precipitation; chitosan with selective adsorption is taken as a clarifier of the water extract of ginkgo leaves. Flocculation is carried out for removing impurities before adopting the alcohol precipitation method of the water extract of ginkgo leaves to extract crude flavonoids and glycoside; a selective flocculation method is adopted to purify impurities of the water extract of ginkgo leaves. The crude flavonoids and glycoside processed by taking chitosan as clarifier of the invention are bright yellow, have an obviously superior quality to the crude flavonoids and glycoside processed by a traditional method and are suitable for pharmacy.

Description

technical field [0001] The invention relates to a method for extracting medicinal materials, in particular to a method for extracting and purifying active ingredients of traditional Chinese medicine. Background technique [0002] At present, the common method of extracting and purifying drugs in traditional Chinese medicine pharmaceutical enterprises is the water extraction and alcohol precipitation method. The water extraction and alcohol precipitation method uses water as a solvent to decoct and finely extract Chinese medicinal materials, and then uses ethanol as a clarifying agent to decoct the water extract. Clarification treatment removes most of the polysaccharides, proteins, resins, etc. in the Chinese medicine water extract, and finally recovers ethanol to obtain a clear and transparent extract solution. This method is suitable for Chinese medicinal materials whose active ingredients are stable to heat, soluble in water, and soluble in a certain concentration of etha...

AI Technical Summary

Problems solved by technology

Although the alcohol precipitation method can be used to obtain a clear active ingredient solution, there are also disadvantages such as poor stability of the finished product, large ethanol consumption, complicated process, high cost and serious waste of resources.

While clarifying the medicinal liquid, some alcohol-insoluble macromolecular active ingredients (such as proteins and some polysaccharides) in traditional Chinese medicine are removed as impurities, and these ingredients, especially polysaccharides, have been shown to enhance immunity and immunity through pharmacological, immunological and clinical studies. Wide range of physiological activities, it is difficult to guarantee the effectiveness of the finished preparation and the stability of the finished product is poor

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