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Partial gradient pore space structure artificial arthrosis prosthesis and method of preparing the same

A pore structure and artificial joint technology, applied in prostheses, joint implants, joint implants, etc., can solve problems such as mechanical properties of damaged prostheses

Inactive Publication Date: 2008-09-03
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to address the deficiencies of the prior art, to provide an artificial joint prosthesis with a local gradient pore structure and a preparation method thereof, so as to overcome the problem of damage to the mechanical properties of the prosthesis itself in the process of preparing the surface porous structure of the artificial joint prosthesis. Insufficient, provide space for the growth of human cells and tissues, promote the growth of new tissue and joint prosthesis, and realize the biological fixation of the prosthesis

Method used

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  • Partial gradient pore space structure artificial arthrosis prosthesis and method of preparing the same
  • Partial gradient pore space structure artificial arthrosis prosthesis and method of preparing the same

Examples

Experimental program
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Effect test

Embodiment 1

[0037] First, spread the spherical titanium powder with a diameter of 100 μm on a titanium plate with a length of 30 mm, a width of 20 mm, and a thickness of 3 mm, and spread 3 layers, and then spread 3 layers of spherical titanium powder with a diameter of 200 μm, and finally spread a layer of titanium powder with a diameter of 300μm spherical titanium powder; put the above-mentioned titanium plate covered with spherical titanium powder into a vacuum sintering furnace for high-temperature sintering. The vacuum degree of the sintering furnace is 1×10 -3 Pa, the furnace temperature is room temperature, the furnace temperature is raised to 1200°C, and the temperature rise rate is 5°C / min. During the sintering process, a pressure of 5 MPa is applied to the titanium plate covered with spherical powder, and the heat preservation and pressure are kept for 2 hours. After that, the furnace Cool the furnace to room temperature to obtain a titanium plate with a gradient pore structure on...

Embodiment 2

[0039] First, spread the spherical titanium powder with a diameter of 200 μm on a titanium plate with a length of 50 mm, a width of 40 mm, and a thickness of 5 mm, and spread one layer, and then spread another layer of spherical titanium powder with a diameter of 300 μm, and finally spread a layer of titanium powder with a diameter of 500μm spherical titanium powder; put the above-mentioned titanium plate covered with spherical titanium powder into a vacuum sintering furnace for high-temperature sintering. The vacuum degree of the sintering furnace is 1×10 -3 Pa, the furnace temperature is room temperature, the furnace temperature is raised to 1400°C, and the heating rate is 10°C / min. During the sintering process, a pressure of 2 MPa is applied to the titanium plate covered with spherical powder, and the heat preservation and pressure are maintained for 1h. After that, the furnace Cool the furnace to room temperature to obtain a titanium plate with a gradient pore structure on ...

Embodiment 3

[0041]First, spread the spherical titanium powder with a diameter of 150 μm on a titanium plate with a length of 40 mm, a width of 30 mm, and a thickness of 4 mm, and spread 2 layers, then spread 2 layers of spherical titanium powder with a diameter of 250 μm, and finally spread a layer of titanium powder with a diameter of 400μm spherical titanium powder; put the above-mentioned titanium plate covered with spherical titanium powder into a vacuum sintering furnace for high-temperature sintering. The vacuum degree of the sintering furnace is 1×10 -3 Pa, the furnace temperature is room temperature, the furnace temperature is raised to 1300°C, and the heating rate is 7.5°C / min. During the sintering process, a pressure of 1.5MPa is applied to the titanium plate covered with spherical powder. Cool the furnace to room temperature to obtain a titanium plate with a surface gradient pore structure; use laser welding technology to weld the above-mentioned titanium plate with a surface gr...

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Abstract

The invention relates to an artificial joint prosthesis with a partial gradient pore structure and a preparation method thereof, and belongs to the biomedical engineering field. The prosthesis comprises a prosthesis handle and a gradient pore structure body; the gradient pore structure body is welded on a presetting position of the prosthesis handle; the gradient pore structure body comprises a metal titanium plate, a first metal titanium ball, a second metal titanium ball, and a third metal titanium ball; the sizes of the first metal titanium ball, the second metal titanium ball and the third metal titanium ball become larger, and the three metal titanium balls are sintered on the metal titanium plate. The method sinters spherical metal powders on the metal titanium plate in a layered way through the sintering process to gain the gradient pore structure body which is then welded on the presetting position of the joint prosthesis. The artificial joint prosthesis not only prevents the prosthesis handle from high-temperature heat treatment process, keeps good high-strength mechanical property, but also gains proper gradient pore structure, provides space to cell and tissues for the long-term embedding, promotes the ankylosing between new formed bone tissues and host bones, and realizes the biological fixation of the prosthesis; in addition, the artificial joint prosthesis can be applied to the restoration of joint injuries in clinic.

Description

technical field [0001] The invention relates to an orthopedic implant prosthesis in the technical field of biomedical engineering and a preparation method thereof, in particular to an artificial joint prosthesis with a local gradient pore structure and a preparation method thereof. Background technique [0002] Artificial joint replacement is a common surgical method for clinical treatment of joint injuries caused by trauma or disease, and the clinical application effect is good. The mechanical and biological properties of artificial joints are the key factors affecting its clinical effect in repairing joint damage. Joint prostheses made of metal materials such as stainless steel, titanium and their alloys usually have good mechanical properties, and after being implanted in the human body, they can meet the force requirements of patients during daily activities. Although titanium and its alloys have good corrosion resistance and biocompatibility. However, the prostheses o...

Claims

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Application Information

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IPC IPC(8): A61F2/30A61L27/06C22C14/00B22F9/00B22F3/00B23K26/00
CPCA61F2/30767A61F2002/30001
Inventor 李祥王成焘
Owner SHANGHAI JIAO TONG UNIV
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