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Composition containing lactase and vitamin D

A vitamin and composition technology, applied in the field of compositions containing lactase and vitamin D, can solve problems such as poor solubility, cumbersome methods, and indigestibility

Inactive Publication Date: 2008-10-15
郭炳华 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Lactose has the following three physical characteristics: 1. Poor solubility: This is the main problem in dairy product processing
2. Low sweetness: the sweetness of α-state lactose is only 16-18 of the sweetness of sucrose (converted with sucrose as 100)
3. Indigestible: the absorption efficiency of lactose is only 1 / 32 of that of glucose
When people take lactase, they take vitamin D in addition. The method is cumbersome and brings a lot of inconvenience to the users.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1 Compound lactase vitamin D powder is prepared from the following formula (containing 60 mg / bag of lactase and 5 μg / bag of vitamin D)

[0019] Specification 0.5g: lactase 60mg and vitamin D 5μg

[0020] Component amount (g):

[0021] Lactase 120g

[0022] Vitamin D 3 Powder 3.6g (equivalent to 10mg vitamin D)

[0023] Starch 870g

[0024] Micronized silica gel 6.4g

[0025]

[0026] Made into 1000g

[0027] Preparation:

[0028] 1. Take raw materials lactase and vitamin D 3 Powder, diluent, and glidant are respectively crushed into fine powder and passed through a 120-mesh sieve for later use;

[0029] 2. Take the above crushed raw materials lactase and vitamin D 3 Powder, diluent, and glidant are mixed, and sieved to fully mix evenly;

[0030] 3. After passing the inspection, pack it into bags (0.5g per bag), and you can get it.

Embodiment 2

[0031] Example 2 Compound lactase vitamin D tablets are prepared from the following formula (containing 60 mg / tablet of lactase and 5 μg / tablet of vitamin D)

[0032] Specification 0.3g: lactase 60mg and vitamin D 5μg

[0033] Component amount (g):

[0034] Lactase 60g

[0035] Vitamin D 3 Powder 1.8g (equivalent to 5mg vitamin D)

[0036] Microcrystalline Cellulose 90g

[0037] Mannitol 126g

[0038] Croscarmellose Sodium 9g

[0039] Hypromellose 10.2g

[0040] Micronized silica gel 0.6g

[0041] Magnesium Stearate 2.4g

[0042]

[0043] Made into 1000 pieces

[0044] Preparation:

[0045] 1. Active ingredients lactase, vitamin D 3 Powder and all auxiliary materials pass through a 100-mesh sieve for later use, weigh the microcrystalline cellulose, mannitol and disintegrant in the formula, and mix evenly;

[0046] 2. Weigh the lactase and vitamin D in the above formula 3 powder, it is added to the mi...

Embodiment 3

[0051] Example 3 Compound lactase vitamin D capsules were prepared from the following formula (containing lactase 90 mg / capsule, vitamin D 5 μg / tablet)

[0052]Specification 0.3g: lactase 90mg and vitamin D 5μg

[0053] Component amount (g):

[0054] Lactase 90g

[0055] Vitamin D 3 Powder 1.8g (equivalent to 5mg vitamin D)

[0056] Starch 75g

[0057] Microcrystalline Cellulose 120g

[0058] Sodium carboxymethyl starch 14.2g

[0059] 5% PVP70% ethanol solution appropriate amount

[0060] Magnesium Stearate 1.5g

[0061]

[0062] Makes 1000 capsules

[0063] Preparation:

[0064] 1. Grind the raw and auxiliary materials into fine powder and pass through a 100-mesh sieve for later use;

[0065] 2. Weigh the starch, microcrystalline cellulose and disintegrant of the formula, and mix them evenly;

[0066] 3. Weigh the lactase and vitamin D in the above formula 3 powder, add to the mixing accessories and mix evenly;

[0067] ...

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Abstract

The invention relates to a composition mainly containing lactase and vitamin D. The composition is mainly used for improving lactose intolerance and promoting calcium absorption. The composition is mixed with proper adjuvants, and then preapred into a plurality of oral products such as conventional tablet, effervesce, buccal tablets, milk tablet, orally disintegrating tablet, granule, effervescent granule, powder, capsule and soft capsule.

Description

technical field [0001] The invention relates to a composition containing lactase and vitamin D, the main function of which is to improve lactose intolerance and promote calcium absorption of human body. Background technique [0002] Lactose is the main carbohydrate in milk, accounting for about 4.4% of milk (about 7.2% in human milk). Lactose is a disaccharide in which D-glucose (Glucose) and D-galactose (Galactose) are bonded by β-1,4. Lactose only exists in the milk of mammals, and is the most important energy source for human infants, but not all mammals contain lactose (for example, the milk of sea animals such as whales and seals does not contain lactose. lactose). Lactose has the following three physical characteristics: 1. Poor solubility: This is the main problem when dairy products are processed. 2. Low sweetness: the sweetness of α-state lactose is only 16-18 of the sweetness of sucrose (calculated as 100 of sucrose). 3. Indigestibility: The absorption efficien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61P3/00A61P3/02A61K31/592A61K31/593
Inventor 郭炳华
Owner 郭炳华
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