Chinese sapium bark seed extract and preparation method thereof

An extract and seed technology, applied in the field of tallow seed extract and its preparation, can solve the problems of poor tumor effect and the like

Inactive Publication Date: 2009-05-20
蒋爱芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The object of the present invention is to provide a kind of Chinese tallow tree seed extract and its preparation method, and described this kind o...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Chinese tallow tree seed powder plus 5 times the amount of 95% ethanol for reflux extraction for 1 hour, the filtered residue plus 4 times the amount of 95% ethanol for reflux extraction for 1 hour, filtered, 4 times the amount and repeated extraction once to combine the filtrate three times, 60 ° C, 700mmHg Recover ethanol, concentrate until there is almost no ethanol smell, add water to 0.8 times the weight of the crude drug, add an equal amount of petroleum ether (60-90°C) for extraction, recover the crude extract after the petroleum ether layer, and the yield is about 40%.

Embodiment 2

[0019] Crude drug powder plus 5 times the amount of 85% ethanol reflux extraction for 1.5 hours, filtered residue plus 4 times the amount of 85% ethanol reflux extraction for 1 hour, filtered, 4 times the amount of repeated extraction once combined filtrate three times, 60C, 700mmHg to recover ethanol , concentrated to almost no ethanol smell, add water to 1.0 times the weight of the crude drug, add an equal amount of petroleum ether (30-60°C) for extraction, recover the crude extract after the petroleum ether layer, and the yield is about 38%.

[0020] Implementation column 3:

[0021] Recipe: Chinese tallow tree seed extract 2.5g

[0022] Lactose 6.0g

[0023] Microcrystalline Cellulose 2.0g

[0024] Magnesium stearate 0.3g

[0025] The above-mentioned ingredients are uniformly mixed to form granules, passed through a 20-80 mesh sieve, dried at 40-80°C, and pressed into tablets.

Embodiment 4

[0027] Recipe: Chinese tallow tree seed extract 2.0g

[0028] Starch 4.0g

[0029] Microcrystalline Cellulose 3.0g

[0030] Talc powder 0.5g

[0031] Mix the above ingredients evenly to make granules, pass through a 20-80 mesh sieve, dry at 40-80°C, and pack into No. 0-3 capsules.

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Abstract

The invention provides a sapium sebiferum seed extract. Sapium sebiferum seeds are pulverized, are extracted through an alcoholic solution and are extracted through an organic solvent with low polarity to obtain the sapium sebiferum seed extract. Antitumor experiments on animals prove that the extract has obvious inhibiting function on various tumors.

Description

Technical field: [0001] The invention relates to the field of traditional Chinese medicine pharmacy, in particular to a Chinese tallow tree seed extract and a preparation method thereof. Background technique: [0002] Sapium sebiferum (L.) Roxb. is a plant of Sapium sebiferum in Euphorbiaceae. It is a common traditional Chinese medicine in my country. It uses root bark, bark, stems and leaves as medicine, and it is relatively rare to use seeds as medicine. The root bark and bark can be collected in four seasons, cork removed, sliced ​​and dried; stems and leaves are mostly used fresh or dried, and can be collected throughout the year; seeds are harvested in autumn. According to the "National Compilation of Chinese Herbal Medicine", this product is bitter in nature and slightly warm. Go into lung, spleen, kidney, large intestine channel. It is slightly poisonous. Function cures mainly for parasite killing, detoxification, diuretic, laxative. For schistosomiasis, liver cir...

Claims

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Application Information

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IPC IPC(8): A61K36/47A61P35/00A61K131/00
Inventor 蒋爱芳
Owner 蒋爱芳
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