Chinese medicine granule containing Huangyangning and preparation method thereof
A technology of traditional Chinese medicine granules and Huang Yang Ning is applied in the field of traditional Chinese medicine granules containing Huang Yang Ning and its preparation. Small, regular particle size distribution effect
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Embodiment 1
[0045] Take an appropriate amount of Huang Yang Ning;
[0046] The preparation of master batch: get the weight ratio of dextrin and starch to be 1: 1 mixture and pass through 200 mesh sieves, wherein 65% are put into the side spraying pot of fluidized bed as bottom material, and starch is added with water to prepare starch slurry (15%) Spray it in as slurry, and screen out small particles (particle size of 180-250μ) as the mother nucleus, then put the mother nucleus into the pot, continue to spray starch slurry, and at the same time remove the remaining 35% of dextrin from the dusting gun Sprinkle with the fine powder of starch to make the particle size of the mother nucleus grow, and screen out the master batch with a particle size of 450μ-600μ for use.
[0047] Preparation of product: take 450g of masterbatch, 50g of microcrystalline cellulose (200 mesh), 6000 polyethylene glycol (heated and melted) 500 g, Huang Yang Ning 320g; add microcrystalline cellulose and micro-powde...
Embodiment 2
[0049] Take an appropriate amount of Huang Yang Ning;
[0050] The preparation of master batch: get the mixture of micropowder silica gel and chitosan weight ratio of 1: 1 and pass through a 200 mesh sieve, 65% of which is put into the side spray pot of the fluidized bed as the bottom material, and PVP K30 is added with water, extract, and prepared. Adhesion-forming agent - sprayed in as slurry, and screened out small particles with a particle size of 120-180μ as the mother nucleus, then put the mother nucleus into the pot, continued to spray starch slurry, and at the same time removed the remaining 35% from the dusting gun The micro-powder silica gel and the fine powder of chitosan are sprinkled in, so that the particle size of the mother nucleus grows, and the master batch with a particle size of 200μ-300μ is selected for use.
[0051] Product preparation: take 300g of masterbatch, 250g of microcrystalline cellulose (200 mesh), 14g of micropowder silica gel, and 200g of buxu...
Embodiment 3
[0053] Take an appropriate amount of Huang Yang Ning;
[0054] The preparation of master batch: get the mixture of dextrin and starch weight ratio of 1: 1 to cross 200 mesh sieves, wherein 65% is put into the side spraying pot of fluidized bed as bottom material, and starch, extract (after being folded to dry, account for mother batch) 15% of the weight of the grains), add water to prepare a slurry and spray it, and sieve out small particles (with a particle size of 180 to 250 μ) as the parent core, then put the parent core into the pot, continue to spray the starch slurry, and at the same time from the dusting gun. Sprinkle the remaining 35% fine powder of dextrin and starch to make the particle size of the parent nucleus grow, and screen out the master batch with a particle size of 300 μ to 400 μ for use.
[0055] Preparation of product: take 450g of masterbatch, 50g of microcrystalline cellulose (200 mesh), 6000 polyethylene glycol (heated and melted) 500 g, 1000g of Huang...
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