Method for continuously extracting effective ingredients from Semen cassiae under high pressure

An active ingredient, high-pressure extraction technology, which is applied to medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, pharmaceutical formulations, etc. problem, to achieve the effect of many active ingredients, avoiding denaturation and high extraction rate

Inactive Publication Date: 2009-08-12
SOUTH CHINA NORMAL UNIVERSITY
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the extraction methods of natural medicines include cooking method, reflux extraction, low temperature impregnation, percolation extraction, supercritical CO 2 Extraction, microwave extraction, and ultrasonic extraction, but the technical effects are not satisfactory, such as: the biological activity and pharmacological activity of the cassia seed extract are low; the extraction rate of the active ingredients of the cassia seed is low; the extraction time is long and the energy consumption is high; multiple extractions are required In order to fully extract the active ingredients; multiple extractions are required, and the

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for continuously extracting effective ingredients from Semen cassiae under high pressure
  • Method for continuously extracting effective ingredients from Semen cassiae under high pressure
  • Method for continuously extracting effective ingredients from Semen cassiae under high pressure

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0048] Example 1:

[0049] (1) Crushing: crush the cassia seed to 40-60 mesh;

[0050] (2) Soaking: Cassia seed and 60% ethanol are mixed and soaked for 35 minutes at a material-to-liquid ratio of 1:15 (g / ml);

[0051] (3) High-pressure extraction: The material liquid obtained in step (2) is sent to the high-pressure extractor through a thick slurry pump, and the material liquid is continuously circulated through the annular working gap of the high-pressure extractor under the action of high pressure of 50Mpa. Impact on the collision ring in the high-pressure extractor, the continuous cycle process lasts for 10 minutes, completely rupture the cell wall of the cassia seed, and the active ingredients diffuse in the solvent;

[0052] (4) Solid-liquid separation: take out the high-pressure processed material and liquid, first send it to the horizontal centrifuge by the thick slurry pump for solid-liquid separation, and obtain the extract and the slag respectively. After testing, the e...

Example Embodiment

[0054] Example 2:

[0055] (1) Crushing: crush the cassia seed to 40-60 mesh;

[0056] (2) Soaking: Cassia seed and 70% ethanol are mixed and soaked for 30 minutes at a material-to-liquid ratio of 1:20 (g / ml);

[0057] (3) High-pressure extraction: The material liquid obtained in step (2) is sent to the high-pressure extractor by a thick slurry pump, and the material liquid is continuously circulated through the annular working gap of the high-pressure extractor under the action of high pressure of 60Mpa to achieve high speed Impact on the collision ring in the high-pressure extractor, the continuous cycle process lasts for 30 minutes, completely rupture the cell wall of the cassia seed, and the active ingredients diffuse in the solvent;

[0058] (4) Solid-liquid separation: take out the high-pressure processed material and liquid, first send it to the horizontal centrifuge by the thick slurry pump for solid-liquid separation, obtain the extract and the residue, and then squeeze t...

Example Embodiment

[0060] Example 3:

[0061] (1) Crushing: crush the cassia seed to 40-60 mesh;

[0062] (2) Soaking: Cassia seed mixed with 80% ethanol at a material-to-liquid ratio of 1:30 (g / ml) and soaked for 30 minutes;

[0063] (3) High-pressure extraction: The material liquid obtained in step (2) is sent to the high-pressure extractor through a thick slurry pump, and the material liquid is continuously circulated through the annular working gap of the high-pressure extractor under the action of high pressure of 50Mpa. Impact on the collision ring in the high-pressure extractor, the continuous cycle process lasts for 10 minutes, completely rupture the cell wall of the cassia seed, and the active ingredients diffuse in the solvent;

[0064] (4) Solid-liquid separation: take out the high-pressure processed material and liquid, first send it to the horizontal centrifuge by the thick slurry pump for solid-liquid separation, obtain the extract and the residue, and then squeeze the residue with a f...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a method for continuously extracting active ingredients of cassia seed at high pressure, comprising the following steps: (1) breaking: the cassia seed is broken to particles with 30-80 meshes; (2) soaking: the cassia seed and ethanol are mixed according to the material-to-liquid ratio of 1:10-30 for soaking for 30-60 minutes; (3) high-pressure extraction: material liquid obtained in the step (2) is sent to a high-pressure extractor, the material liquid continuously passes an annular working gap of the high-pressure extractor under the action of 30-90Mpa high pressure, so as to collide on a collision ring in the high-pressure extractor at high speed, break cell walls of the cassia seed and lead the active ingredients to be dispersed in solvent; (4) solid-liquid separation: the material liquid after the high-pressure treatment is taken out, and the solid-liquid separation is carried out for obtaining extract liquid and material residue respectively. The process has simple and safe operation.

Description

technical field [0001] The invention relates to a method for extracting Chinese herbal medicines, in particular to a method for continuously extracting active components of Semen Cassiae under high pressure. Background technique [0002] Cassia is the dry mature seed of Cassia obtusifolia L. or C. tora L. of the leguminous plant. It is a commonly used traditional Chinese medicine in clinical practice. It is listed as the top grade in "Shen Nong's Materia Medica". Modern studies have proved that cassia seed has the activities of lowering blood pressure, lowering blood fat, protecting liver and inhibiting bacteria. At the same time, it can be used as food and a good raw material for health drinks. Therefore, Semen Cassiae has extensive research, utilization and development prospects in terms of medicine and health care. At present, the extraction methods of natural medicines include cooking method, reflux extraction, low temperature impregnation, percolation extraction, super...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/482A61P1/16A61P3/06A61P9/10A61K131/00
Inventor 梁勇徐明忠
Owner SOUTH CHINA NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap