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Tea oral tablet and preparation method thereof

A technology for oral tablets and theaflavins, which can be used in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. carry effect

Active Publication Date: 2009-09-02
杭州英仕利生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, tea extract products in the domestic market mostly use tea polyphenols as the main component, and theaflavins with stronger efficacy are difficult to extract, so products with theaflavins as the main component are rare in the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0027] The preparation method of above-mentioned tea oral tablet, comprises the following steps:

[0028] 1. Take materials according to the following mass percentages:

[0029] Theaflavins 5-30%

[0030] Tea polyphenols 15-30%

[0031] Filler 20-60%

[0032] Flavor 5-10%

[0033] Disintegrant 10-15%

[0034] Binder 1-3%.

[0035] 2. Mix theaflavins, tea polyphenols, fillers, flavoring agents and disintegrants, crush them, pass through a 40-100 mesh sieve, and mix in a mixer for 20-50 minutes;

[0036] 3. Add ethanol with a volume ratio of 95% to moisten and granulate, pass through a 16-40 mesh sieve; dry at 40-70°C for 2-5 hours, granulate through a 40-100 mesh sieve, and cool.

[0037] 4. After the granulation, the material is added to the binder and mixed in the sugar coating machine for 20-40 minutes.

[0038] 5. Compression molding by tablet press.

Embodiment 1

[0041] Take 20 parts of theaflavins, 25 parts of tea polyphenols, 38 parts of xylitol, 6 parts of vitamin C, and 10 parts of microcrystalline cellulose, mix and pulverize them, and pass through a 40-mesh sieve. Mix in a mixer for 20 minutes, add 95% ethanol to granulate, pass through a 16-mesh sieve, dry at 50°C for 4 hours, granulate and cool at 80-mesh. After adding 1 part of magnesium stearate for mixing, it is mixed with the granulated material in a water chestnut icing machine for 30 minutes. Tablet press compression molding.

Embodiment 2

[0043] Take 16 parts of theaflavins, 27 parts of tea polyphenols, 46 parts of mannitol, 5 parts of citric acid, and 4 parts of croscarmellose sodium, mix and pulverize them, and pass through a 40-mesh sieve. Mix in a mixer for 30 minutes, add 95% ethanol to granulate, pass through a 16-mesh sieve, dry at 60°C for 3 hours, granulate and cool at 70-mesh. After adding 2 parts of pregelatinized starch and mixing, then mix with the whole material in a water chestnut sugar coating machine for 30 minutes. Tablet press compression molding.

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PUM

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Abstract

The invention discloses a tea oral tablet and a preparation method thereof. The tea oral tablet uses theaflavin and theine-removing tea polyphenol as main raw materials, and filling agent, flavouring agent, bonding agent and disintegrant are added into the main raw materials to prepare the oral tablet product. The product has the physiologic function of the theaflavin and the tea polyphenol, is favorable to the oxidation resistance of a human body to remove free radicals for keeping the function of the human body and is easy to take and convenient to carry.

Description

technical field [0001] The invention relates to a health care product, in particular to an oral tablet containing tea extracts such as theaflavins and tea polyphenols and a preparation method thereof. Background technique [0002] Studies have shown that the active ingredients in tea have health care functions. Theaflavins and tea polyphenols are the main active substances in tea. Theaflavins and tea polyphenols have the functions of anti-oxidation and scavenging oxygen free radicals, sterilization and anti-virus, protection and repair of DNA, enhancement of immune function, regulation of physiology (lowering blood fat, blood sugar and blood pressure), detoxification, anti-aging, anti-radiation and other functions. [0003] Although drinking tea directly can also absorb theaflavins and tea polyphenols, because the content of theaflavins and tea polyphenols in tea extracts is low, the functional substances in the tea obtained by drinking tea directly are far less than what t...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61K9/20A61K47/40A61K47/38A61K47/36A61P39/06A61P37/04A61P31/04A61P31/12A61P39/02A61P3/06A61P3/10A61P9/12A61K31/353
Inventor 屠幼英
Owner 杭州英仕利生物科技有限公司
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