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Fish skin collagen peptide with whitening effect and preparation process and application thereof

A collagen peptide and fish skin technology, applied in the field of fish skin collagen peptide, can solve problems such as limited bioavailability, and achieve the effects of high safety, broad market prospects and excellent wettability

Active Publication Date: 2012-01-04
武汉天天好生物制品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the collagen peptides currently on the market are mainly composed of 30 to 100 amino acids to form polyamino acids. The average molecular weight is 3000-10000Da, and its bioavailability is limited.

Method used

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  • Fish skin collagen peptide with whitening effect and preparation process and application thereof
  • Fish skin collagen peptide with whitening effect and preparation process and application thereof
  • Fish skin collagen peptide with whitening effect and preparation process and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] 1. Thaw 10kg of frozen fish skin, wash the residual meat and blood, drain and weigh about 9kg of fish skin, add 54L of natural water and 270g of calcium hydroxide, mix and soak for 5 days (stirring twice a day), after 6 days , washed with natural water (200L, time-consuming 2h) until neutral, drained and weighed to obtain about 6 kg of fish skin (washed fish scales discarded) and refrigerated for later use.

[0036] 2. Weigh 1 kg of fish skin for refrigerated use on a platform scale, add 5 L of distilled water according to the material-to-liquid ratio of 1:5, and denature under high pressure at 121°C for 60 minutes.

[0037] 3. Remove the fish skin residue by filtering with double-layer gauze, in a constant temperature water bath at 50°C, adjust the pH value to 7.0, add 7g of Bacillus subtilis alkaline protease, then add 7g of bromelain and 7g of neutral protease, start timing from the addition of Bacillus subtilis alkaline protease , A total of automatic stirring enzym...

Embodiment 2

[0043] 1. Thaw 9kg of frozen fish skin, wash the remaining meat and blood, drain and weigh about 8kg of fish skin, add 40L of natural water and 240g of calcium hydroxide, mix and soak for 7 days (stir twice a day), after 7 days , washed with natural water (200L, time-consuming 2h) until neutral, drained and weighed to obtain about 5.5 kg of fish skin (washed fish scales were discarded) and refrigerated for later use.

[0044] 2. Weigh 1 kg of fish skin for refrigerated use on a platform scale, add 5.5 L of distilled water according to the material-to-liquid ratio of 1:5.5, and denature at 121°C for 80 minutes under high pressure.

[0045] 3. Double-layer gauze filter to remove fish skin residue, 50 ℃ constant temperature water bath, adjust the pH value to 8.0, add 9g Bacillus subtilis alkaline protease, then add 9g bromelain and 9g neutral protease, start timing from the addition of Bacillus subtilis alkaline protease , A total of 5.5h of enzymatic hydrolysis with automatic stir...

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PUM

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Abstract

The invention discloses fish skin collagen peptide with the whitening effect and a preparation process and application thereof, and in particular relates to fish skin collagen peptide obtained by using alkali solution to process fish skin, using a protease hydrolysis method to process the fish skin and performing a series of technical treatment of decoloration, deodorization and impurity removal on hydrolysis liquid and a preparation process thereof and application of the fish skin collagen peptide as a cosmetic or an additive of skin-care cosmetics. Compared with the common collagen peptide,the fish skin collagen peptide has high content of small molecular peptides, lower ash content, high protein content, and greatest whitening effect among like products in the market; and the fish skin collagen peptide as the cosmetic or the additive of the skin-care cosmetics without toxic and side effect has wide development prospect.

Description

technical field [0001] The invention relates to a fish skin collagen peptide with whitening effect, its preparation process and application. Specifically, the present invention relates to a kind of whitening effect obtained by treating fish skin with alkaline solution, then treating the fish skin with protease hydrolysis, and performing a series of decolorization, deodorization and impurity removal on the hydrolyzed solution. Fish skin collagen peptide, its preparation process and its use as an additive for cosmetics or skin care products. Background technique [0002] Collagen is a kind of fibrous protein in organisms, which mainly exists in tissues such as skin, bone, cartilage and tendon, accounting for 25% to 33% of the total protein content of human or other animals. Collagen is widely used in the field of biomedical materials because of its excellent biological properties. Therefore, how to extract high-purity, high-yield bioactive collagen has always been a topic of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K5/083C07K7/06C07K1/14C12P21/06A61K8/65
Inventor 陈栋梁
Owner 武汉天天好生物制品有限公司
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