Porcine compound astragalus polysaccharide injection and preparation method thereof

A technology of astragalus polysaccharides and injections, applied in medical preparations containing active ingredients, pharmaceutical formulas, cyclic peptide components, etc., can solve the problems of poor control of diseases, inconvenience for matching breeders, poor treatment, etc. , to achieve the effect of reducing the drug resistance of pathogenic microorganisms, reducing the probability of drug resistance, and improving the body's resistance

Inactive Publication Date: 2009-12-30
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the widespread incidence of this type of disease recently, because it cannot be judged well clinically, a sin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0019] Example 1

[0020] (1) Take 25L of water for injection, add 3kg of sodium salicylate, stir to dissolve, then add 1kg of methaquine, and stir until all is dissolved.

[0021] (2) Take 5 kg of 95% ethanol, add 10 kg of colistin sulfate and stir until it becomes a paste, then add 20L of water for injection at about 80°C, stir to dissolve and cool to about 50°C.

[0022] (3) Take 10L of water for injection, dissolve 0.18kg of atropine sulfate and 0.5kg of astragalus polysaccharide.

[0023] (4) Combine the solutions prepared in steps (1), (2) and (3), add 30kg of propylene glycol, and then add water for injection to 100L, stir evenly, keep it for 15-20min, and use a mass percentage concentration of 40% The pH value of the sodium hydroxide solution or the hydrochloric acid solution with a concentration of 10% by volume percentage is adjusted to 5.58, and the compound astragalus polysaccharide injection for pigs of the present invention can be prepared after the drug solution is ...

Example Embodiment

[0024] Example 2

[0025] (1) Take 25L of water for injection, add 21kg of sodium salicylate, stir to dissolve, then add 7kg of methaquine, and stir until all is dissolved.

[0026] (2) Take 5 kg of 95% ethanol, add 2 kg of colistin sulfate and stir until it becomes a paste, then add 20 L of water for injection at about 80°C, stir to dissolve and cool to about 50°C.

[0027] (3) Take 10L of water for injection, dissolve 0.18kg of atropine sulfate and 5kg of astragalus polysaccharide.

[0028] (4) Combine the solutions prepared in steps (1), (2) and (3), add 30kg of propylene glycol, and then add water for injection to 100L, stir evenly, keep it for 15-20min, and use a mass percentage concentration of 40% The pH value of the sodium hydroxide solution or the hydrochloric acid solution with a concentration of 10% by volume percentage is adjusted to 6.20, and the compound astragalus polysaccharide injection for pigs of the present invention is prepared after the drug solution is clear...

Example Embodiment

[0029] Example 3

[0030] (1) Take 25L of water for injection, add 9kg of sodium salicylate, stir to dissolve, then add 3kg of methaquine, and stir until all is dissolved.

[0031] (2) Take 5 kg of 95% ethanol, add 8 kg of colistin sulfate and stir until it becomes a paste, then add 20L of water for injection at about 80°C, stir to dissolve and cool to about 50°C.

[0032] (3) Take 10L of water for injection, dissolve 0.18kg of atropine sulfate and 0.8kg of astragalus polysaccharide.

[0033] (4) Combine the solutions prepared in steps (1), (2) and (3), add 30kg of propylene glycol, and then add water for injection to 100L, stir evenly, keep it for 15-20min, and use a mass percentage concentration of 40% The pH value of the sodium hydroxide solution or the hydrochloric acid solution with a concentration of 10% by volume percentage is adjusted to 5.22, and the compound astragalus polysaccharide injection for pigs of the present invention can be prepared after the drug solution is c...

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Abstract

The invention discloses a porcine compound astragalus polysaccharide injection and a preparation method thereof. The invention aims to provide a compound astragalus polysaccharide injection which treats the diarrhea caused by compound infection of porcine bacteria and viruses, has quick response, treats both principal and secondary aspects of diseases, reduces the applied times of the medicament and has convenient medicament use, and a preparation method with simple process and easy realization. Each 100L of injection comprises 0.5 to 5kg of astragalus polysaccharide, 1 to 7kg of maquindox, 3 to 21kg of sodium salicylate, 2 to 10kg of colistin sulfate, 0.18kg of atropine sulfate, 30kg of propanediol, 5kg of 95 percent ethanol, and the balance of water for injection. The injection synchronously takes effect from many aspects through the reasonable proportioning of the consumption of various components of several medicaments, has quick response on the treatment of the diarrhea caused by the compound infection of the porcine bacteria and viruses, treats both principal and secondary aspects of diseases, reduces the drug resistance of bacteria, improves the resistance of organisms, and ensures that the recovery of pigs is accelerated. At the same time, a compound preparation of the invention is the injection and has convenient use.

Description

technical field [0001] The invention relates to a compound astragalus polysaccharide injection for pigs and a preparation method thereof. Background technique [0002] Porcine bacterial and viral mixed infectious diarrhea is a common disease in pigs. It is mainly caused by one or several pathogens such as viruses (such as transmissible gastroenteritis virus, etc.), E. This type of diarrhea may be a viral infection followed by a bacterial infection or a bacterial infection followed by a viral infection. [0003] Due to the widespread incidence of this type of disease recently, because it cannot be judged well clinically, a single treatment method is often adopted, which cannot be treated well. If it is not well controlled, it is easy to cause great losses. Contents of the invention [0004] The purpose of the present invention is to overcome the deficiencies in the prior art, provide a broad-spectrum treatment of diarrhea caused by mixed infection of pig bacteria and viru...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K38/12A61P31/04A61P31/12A61P1/12A61K31/60A61K31/498A61K31/46A61K31/715
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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