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Application of a traditional Chinese medicine in preparing a medicine for reducing inflammatory reaction after PCI

A technology of inflammatory response and traditional Chinese medicine, applied in the field of medicine, can solve the problems of albumin leakage drugs, the application of drugs for inhibiting mast cell degranulation, the preparation of drugs for the prevention and treatment of plateau hypoxia, and the effects have not been reported yet.

Active Publication Date: 2010-03-24
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent application CN1375316A discloses the composition, preparation method and application of the preparation in angina pectoris of coronary heart disease. Applications in the preparation of drugs for preventing and treating senile dementia, drugs for inhibiting albumin leakage, drugs for inhibiting mast cell degranulation, drugs for preventing and treating plateau hypoxia, and drugs for treating acute pancreatitis. The effect of reducing inflammatory factors after PCI has not been reported

Method used

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  • Application of a traditional Chinese medicine in preparing a medicine for reducing inflammatory reaction after PCI
  • Application of a traditional Chinese medicine in preparing a medicine for reducing inflammatory reaction after PCI
  • Application of a traditional Chinese medicine in preparing a medicine for reducing inflammatory reaction after PCI

Examples

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Embodiment 1

[0028] The preparation of embodiment one Qishen Yiqi dripping pill extract

[0029] Take 86.5g of astragalus, 21.3g of salvia miltiorrhiza, 3.5g of notoginseng, 20.6g of jiangxiang, and 30g of polyethylene glycol-6000 as an auxiliary material. Decoct the crushed salvia miltiorrhiza and Panax notoginseng in water twice, adding 7 times the amount of water each time for 2 hours each time, combining the decoction liquid, filtering, and concentrating the filtrate to 900ml, adding 95% ethanol to make the alcohol concentration reach 70%, let it stand for 12-24 hours, filter, recover ethanol, concentrate into an extract with a relative density of 1.32-1.38 (50-60°C); decoct the pulverized Astragalus membranaceus twice with water, adding 6 Double the amount of water, extract for 2 hours and 1 hour in turn, combine the filtrate, and when concentrated to about 1500ml, add 95% ethanol to make the alcohol concentration 60%, let it stand for 12-24 hours, filter, recover ethanol from the fil...

Embodiment 2

[0030] The preparation of embodiment two Qishen Yiqi dripping pills

[0031]Take the Danshen Sanqi extract, Radix Astragali extract and polyethylene glycol-6000 of Example 1, dissolve in a water bath, and after homogenization, add balsamic volatile oil, mix well, move to the dropping pill machine, and make 1000 dropping pills .

Embodiment 3

[0032] The preparation of embodiment three Qishen Yiqi dripping pills

[0033] Get Astragalus 40.6g, Salvia miltiorrhiza 44.8g, Panax notoginseng 11.2g, Jiangxiang 38.6g, adjuvant polyethylene glycol-6000 30g, make 1000 drop pills by the method of embodiment one and embodiment two.

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Abstract

The invention relates to application of a traditional Chinese medicine composition in preparing a medicine for reducing inflammatory reaction after PCI, which is prepared from the following bulk drugsby weight percentage: 22.2 to 66.8 % of radix astragali, 11.6 to 33.4 % of red sage root, 2.5 to 13.5 % of pseudo-ginseng, and 14.5 to 44.3 % of dalbergia heartwood.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Qishen Yiqi dripping pills in the preparation of medicines for reducing inflammation after PCI. Background technique [0002] Percutaneous coronary intervention (PCI) encompasses a variety of methods used to treat heart artery disease. Examples include chest pain caused by reduced blood flow nearby due to deposits of fat, cholesterol, and other blood-borne substances (called lipid plaques), or a heart attack caused by a large blood clot completely blocking an artery. [0003] A typical percutaneous coronary intervention involves guiding a small balloon-tipped catheter from the groin artery to the troubled heart artery (called percutaneous transluminal coronary angioplasty [PTCA], coronary balloon dilation surgery or balloon angioplasty). The balloon inflates to compress the fat plaque and dilate the narrowed coronary artery so that the blood can flow smoot...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61P29/00
Inventor 魏万林张薇朱永宏马洁
Owner TIANJIN TASLY PHARMA CO LTD
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