High-intensity porous bone repair material and method for preparing same

A technology for repairing materials and porous bone, applied in medical science, prosthesis, etc., can solve problems such as restricting the application of bone repair materials, and achieve the effect of improving contradictions, expanding the scope of application, and good pore penetration

Inactive Publication Date: 2012-11-07
HEBEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Bone repair materials, especially bone defect repair materials for large load-bearing parts, require materials with good mechanical properties. Traditional bioceramic bone repair materials mainly include tricalcium phosphate, hydroxyapatite and other glass ceramics. Tricalcium phosphate has good Degradability, hydroxyapatite has good osteoinductive ability, but it has inherent brittleness, which has restricted the application of this type of bone repair material

Method used

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  • High-intensity porous bone repair material and method for preparing same
  • High-intensity porous bone repair material and method for preparing same
  • High-intensity porous bone repair material and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Preparation of bioglass:

[0029] (1) will P 2 o 5 , CaO, Na 2 Grind O and MgO according to the mass ratio of 62:10:15:5.30, grind and mix evenly, add deionized water slowly, stir until no bubbles emerge, and melt at 940°C for 1.5 hours after drying to obtain a milky white block objects, ground into powder;

[0030] (2) Carry out the following heat treatment to the powder: keep warm at 710°C for half an hour, cool to room temperature; keep warm at 745°C for 1 hour, then keep warm at 800°C for 2 hours, and cool with the furnace. bioglass of magnesium salts;

[0031] (3) Add the bioglass whose composition is sodium pyrophosphate and sodium calcium magnesium salt into deionized water, stir constantly, remove the supernatant liquid in the container, repeat several times until the pH of the solution is 8.5, and then a kind of biological glass is made. Glass.

Embodiment 2

[0033] Preparation of bioglass:

[0034] (1) will P 2 o 5 , CaO, Na 2 O and MgO, according to the mass ratio of 41.4:9.8:18:4, grind and mix evenly, slowly add deionized water, stir until no bubbles come out, melt at 980°C for 1 hour after drying, and obtain a milky white block objects, ground into powder;

[0035] (2) Carry out the following heat treatment to the powder: keep warm at 710°C for half an hour, cool to room temperature; keep warm at 740°C for 1 hour, then keep warm at 800°C for 2 hours, and cool with the furnace. The resulting ingredients are sodium pyrophosphate and sodium calcium acid bioglass of magnesium salts;

[0036] (3) Add the bioglass whose composition is sodium pyrophosphate and sodium calcium magnesium salt into deionized water, stir continuously, remove the supernatant liquid in the container, repeat several times until the pH of the solution is 7, and then a kind of biological glass is made. Glass.

Embodiment 3

[0038] Preparation of bioglass:

[0039] (1) will P 2 o 5 , CaO, Na 2 O and MgO, according to the mass ratio of 50:13:12:3.50, grind and mix evenly, add deionized water slowly, stir until no bubbles come out, dry and melt at 900°C for 2 hours to obtain a milky white block objects, ground into powder;

[0040] (2) Carry out the following heat treatment to the powder: keep warm at 720°C for half an hour, cool to room temperature; keep warm at 750°C for 1 hour, then keep warm at 800°C for 2 hours, and cool with the furnace. The resulting ingredients are sodium pyrophosphate and sodium calcium acid bioglass of magnesium salts;

[0041] (3) Add the bioglass whose composition is sodium pyrophosphate and sodium calcium magnesium salt into deionized water, stir constantly, remove the supernatant liquid in the container, repeat several times until the pH of the solution is 8, that is, a biological glass is made. Glass.

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Abstract

The invention discloses a high-intensity porous bone repair material and a method for preparing the same. The method comprises the following: (1) a step of preparing a porous body, which is to use beta-tricalcium phosphate, bio-glass and a stable tetragonal zirconia power as a solid phase, add deionized water into the solid phase, add ammonium polyacrylate serving a dispersant, process the mixture by ball milling to prepare pulp, soak polyurethane foam completely into the pulp, take out the soaked foam, extrude excessive pulp out of the product so as to evenly coat the pulp on the pore walls of the porous body, dry the obtained product, place the dried product in a program control furnace or an electric resistance furnace, film the obtained product at a rising temperature and sinter the filmed product to form the porous body; (2) a step of soaking the obtained porous body in a water solution of NaOH, washing the product with deionized water in the atmosphere of ultra waves and drying the resulting product to obtain the high-intensity porous bone repair material. The high-intensity porous bone repair material of the invention has a high intensity and a high compressive strength, can be widely applied to repair skulls, frontal bones and the like and can also be used to reconstruct scaffolds of cell carriers in tissue engineering and repairing organs.

Description

technical field [0001] The invention relates to a bone repair material and a preparation method thereof, in particular to a high-strength porous bone repair material and a preparation method thereof. Background technique [0002] Bone repair materials, especially bone defect repair materials for large load-bearing parts, require materials with good mechanical properties. Traditional bioceramic bone repair materials mainly include tricalcium phosphate, hydroxyapatite and other glass ceramics. Tricalcium phosphate has good Hydroxyapatite has good osteoinductive ability, but it has inherent brittleness, which has restricted the application of this type of bone repair material. Contents of the invention [0003] The purpose of the present invention is to overcome the deficiencies in the prior art and provide a high-strength porous bone repair material. [0004] The second object of the present invention is to provide a method for preparing a high-strength porous bone repair m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/46A61L27/56C03C3/16
Inventor 王洪水于显著梁春永肖张莹张文娟蔡舒
Owner HEBEI UNIV OF TECH
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