Glycyrrhizic acid removal glycyrrhiza flavonoid and medicament composition thereof

Abstract

The invention provides glycyrrhizic acid removal glycyrrhiza flavonoid for treating a canker disease and a medicament composition thereof. The preparation method comprises the following steps: taking wastewater generated by producing glycyrrhizic acid and waste dregs as raw materials and then carrying out a series of steps like alkalization reaction, separate deacidification, acid-base conversion, macro porous resin absorption and purification and the like. In a prepared sample, the content of the glycyrrhiza flavonoid is high and can maximally reach 98 percent, and the content of the glycyrrhizic acid is very low and is only 0.1-1 percent; and the glycyrrhiza flavonoid is further prepared into various preparations suitable for clinical application. The glycyrrhizic acid removal glycyrrhiza flavonoid and the preparation method thereof adopts the acid-base reaction, conversion and traditional Chinese medicine modern separation and purification technology and has the advantages of novel process, suitable industrialized production and strong practicability.

Description

technical field

[0001] The invention relates to a deglycyrrhizic acid flavonoid and a pharmaceutical composition thereof for treating ulcer disease, belonging to the field of medicine. Background technique

[0002] Ulcer disease is a common chronic systemic disease, divided into gastric ulcer and duodenal ulcer, also known as peptic ulcer. The reason why it is called peptic ulcer is because it was believed that gastric ulcer and duodenal ulcer were formed due to the self-digestion of the mucosa by gastric acid and pepsin. In fact, gastric acid and pepsin are only one of the main reasons for the formation of ulcers. , there are other reasons for the formation of ulcers. Because there are many similarities in the etiology and clinical symptoms of gastric and duodenal ulcers, it is sometimes difficult for doctors to distinguish between gastric ulcers and duodenal ulcers, so they are often diagnosed as peptic ulcers, or gastric and duodenal ulcers . If it is clear that the ul...