Fexofenadine hydrochloride orally disintegrating tablet and preparation method thereof
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A technology for fexofenadine hydrochloride and oral disintegrating tablets is applied in the field of preparation of fexofenadine hydrochloride oral disintegrating tablets, and can solve the problems of slow onset, low bioavailability, poor disintegration and the like, Achieve the effect of fast absorption, high bioavailability and convenient administration
Inactive Publication Date: 2010-06-30
YANGTZE RIVER PHARMA GRP BEIJING HAIYAN PHARMA
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Problems solved by technology
[0005] The dosage forms of fexofenadine products marketed abroad are tablets and capsules, but they have disadvantages such as poor disintegration, slow onset of action and low bioavailability
Method used
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the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Abstract
The invention provides a preparation method of fexofenadine hydrochloride orally disintegrating tablets. Based on the advantages of the orally disintegrating tablet preparation formulation, the product not only overcomes the defects of poor disintegration, slow effect, low bioavailability and the like of the preparation formulations on sale in foreign countries, but also fills a gap in the domestic market, thus adapting to the demand of development of market situation. The medicine has important significance in keeping good health of the people and creating economical and social benefits. The product has simple and easy technique and easily obtained raw and auxiliary materials, is suitable for industrial production, and has good application prospect.
Description
technical field [0001] The invention provides a preparation method of fexofenadine hydrochloride orally disintegrating tablets. Background technique [0002] Fexofenadine Hydrochloride belongs to the third-generation antihistamine without sedative effect. It is the active metabolite of terfenadine in the human body and has a good antihistamine H1 receptor effect. It not only retains the non-sedative properties of the parent compound terfenadine, but also does not have the adverse reactions of terfenadine prolonging the QT interval, paroxysmal ventricular tachycardia and other ventricular arrhythmias. It is used for the treatment of chronic idiopathic urticaria and seasonal allergic rhinitis, suitable for the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria in adults and children over six years old, and can effectively relieve the symptoms caused by seasonal allergic rhinitis. Sneezing, runny nose, itchy nose, palate, and throat, itching, red eye symp...
Claims
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Application Information
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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/445A61K9/20A61P43/00A61P37/08
Inventor 周津梅石和鹏侯鹏李薇常艳艳刘冬曾丽君何夏宜
Owner YANGTZE RIVER PHARMA GRP BEIJING HAIYAN PHARMA
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