Sobering up and liver protecting Chinese medicinal preparation and preparation method thereof

A technology for sobering up and protecting the liver and traditional Chinese medicine, which is applied in pharmaceutical formulations, drug combinations, and medical preparations containing active ingredients, etc., can solve the problems of difficult preservation, easy moisture absorption, complex chemical components, etc., achieves obvious innovation and reduces preparation costs. , the effect of improving yield and quality

Inactive Publication Date: 2010-09-01
FUZHOU UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] Due to the complex chemical composition of Chinese medicinal materials, the extracts prepared by the water extraction process used in traditional Chinese medicine contain flavonoids, saponins, alkaloids and other main medicinal active ingredients for sobering up and protecting the liver, but also contain a large amount of protein, polysaccharides, essential oils, and tannins. , vitamins, inorganic salts and organic acids and other inactive impurities, the product obviously has defects such as easy moisture absorption, difficulty in storage, low purity of active ingredients such as flavonoids, saponins, alkaloids, and low content of active ingredients for sobering up an

Method used

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  • Sobering up and liver protecting Chinese medicinal preparation and preparation method thereof
  • Sobering up and liver protecting Chinese medicinal preparation and preparation method thereof
  • Sobering up and liver protecting Chinese medicinal preparation and preparation method thereof

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preparation example Construction

[0020] The preparation method of the traditional Chinese medicine extract of the present invention is as follows: Pueraria japonica, Hovenia dulcis, Gynostemma pentaphylla, Lvyi citrus aurantium, licorice and gardenia are respectively pulverized into coarse powder, and the final concentration is 9 to 15 times the amount of medicinal materials (W / W). It is a 30%-70% polar organic solvent aqueous solution, extracted 1-3 times at 50°C-80°C, 1-3 hours each time, combined the extracts, filtered, recovered the solvent under reduced pressure, and concentrated in a vacuum to form a traditional Chinese medicine extract. paste.

[0021] The preparation method of the traditional Chinese medicine compound of the present invention is as follows: Pueraria lobata root and Poria cocos are pulverized into fine powder respectively, added to the above-mentioned traditional Chinese medicine extract, mixed evenly, and dried to prepare the Chinese medicine compound for sobering up alcohol and protec...

Embodiment 1

[0027] Pueraria japonica, Hovenia dulcis, Jiaogulan, Lvyi Zhishi, licorice, gardenia and other medicinal materials were respectively crushed to 16-30 mesh coarse powder, according to the formula (25% Pueraria japonica, 30% Hovenia dulcis, 10% Jiaogulan, green Aurantium aurantii 6%, Glycyrrhiza 10%, Gardenia 3%) take materials, add 70% ethanol aqueous solution of 15 times the amount of medicinal materials (W / W), extract at 80°C for 1 hour, filter, and recover under reduced pressure The solvent is concentrated into a hangover-protecting liver traditional Chinese medicine extract, and experiments show that the extraction rate is 10.7%.

[0028] Pueraria lobata and Poria cocos were respectively crushed into fine powders over 100 meshes, taken according to the formula (10% Pueraria lobata, 6% Poria cocos), added to the above-mentioned traditional Chinese medicine extract, mixed evenly, and spray-dried to obtain the Chinese medicine compound for hangover and liver protection.

[002...

Embodiment 2

[0031] Pueraria japonica, Hovenia dulcis, Jiaogulan, Lvyi Zhishi, licorice, gardenia and other medicinal materials were respectively pulverized into coarse powders of 16-30 meshes, according to the formula (25% of Pueraria japonica, 30% of Hovenia dulcis, 3% of Jiaogulan, green Aurantium aurantium 7%, Radix Glycyrrhizae 8%, Fructus Gardeniae 8%) take material, add the 60% ethanol aqueous solution of 13 times medicinal material amount (W / W), leaching 2 times under the condition of 65 ℃, each time 2 hours, The extracts were combined, filtered, the solvent was recovered under reduced pressure, and concentrated into a hangover-protecting liver traditional Chinese medicine extract. Experiments showed that the extraction rate was 10.6%.

[0032] Pueraria lobata and Poria cocos were crushed into fine powders of over 100 mesh respectively, and materials were taken according to the formula (10% of Pueraria lobata root and 6% of Poria cocos), added to the above-mentioned traditional Chin...

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Abstract

The invention relates to a sobering up and liver protecting Chinese medicinal preparation and a preparation method thereof. The Chinese medicinal preparation comprises the following components in percentage by weight: 6 to 50 percent of kudzu vine flower, 6 to 40 percent of trifoliate orange seed, 1 to 18 percent of gynostemma pentaphylla, 1 to 18 percent of Citrus seed, 1 to 18 percent of licorice, 1 to 18 percent of cape jasmine, 3 to 18 percent of kudzu vine root and 3 to 18 percent of tuckahoe. The preparation method comprises the following steps of: crushing the kudzu vine flower, the trifoliate orange seed, the gynostemma pentaphylla, the Citrus seed, the licorice and the cape jasmine into coarse powder; adding water solution of polar organic solvent in the powder for extracting; merging the extract; filtering and performing decompression recovering on the solvent; and concentrating to obtain sobering up and liver protecting Chinese medicinal extractum, and adding the kudzu vine root and the tuckahoe into the extractum to obtain a sobering up and liver protecting Chinese medicinal compound. The purpose of the method is to prepare the sobering up and liver protecting Chinese medicinal preparation safely, simply, reasonably and economically. The product has the advantages of relieving alcoholism, preventing drunkenness and preventing alcoholic liver injury, along with convenient taking, obvious curative effect, no toxic and side effect and the like and is particularly suitable for people who drink for a long time.

Description

Technical field: [0001] The invention relates to a green chemical preparation method for extracting medicinal active ingredients from plants, and more specifically relates to a traditional Chinese medicine medicament for sobering up alcohol and protecting the liver and a preparation method thereof. Background technique: [0002] The human body's catabolism of alcohol is a normal physiological phenomenon. A small amount of ethanol in the body can be catabolized into acetic acid under the action of alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH), and finally converted into acetic acid through oxidation. CO 2 and H 2 O is excreted from the body, but the excess ethanol is easily converted into free radicals because it cannot be metabolized and decomposed in time, causing a series of body dysfunction and symptoms of alcoholism. [0003] A large number of studies have shown that the activation of fat storage cells after long-term drinking plays a major role in ...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P1/16A61P25/32
CPCA23V2002/00
Inventor 陈剑锋郭养浩陈浩
Owner FUZHOU UNIV
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