Medicament for curing dysuria, preparation method and quality control method thereof

A quality control method and drug technology, applied in the direction of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as poor controllability, unreasonable quality control methods, and affect the stability of curative effect, etc., to achieve technological controllable effect

Inactive Publication Date: 2010-09-01
秦皇岛润青制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine is used in the treatment of dysentery. There are many kinds of prescriptions in clinic. However, the controllability of most prescriptions is not good, and the process parameters are not complete, which af...

Method used

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  • Medicament for curing dysuria, preparation method and quality control method thereof
  • Medicament for curing dysuria, preparation method and quality control method thereof
  • Medicament for curing dysuria, preparation method and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0155] Embodiment 1, common tablet of the present invention

[0156] 300 parts of psoralen and 480 parts of motherwort

[0157] 300 servings of Haijinsha, 240 servings of Shanzi Mushroom

[0158] Weigh the above medicinal materials, among which sea ginseng is fried, add 8 times the amount of water each time and steam it twice, the first time is 3 hours, and the second time is 1 hour. Combine the decoctions, filter, and concentrate the filtrate under reduced pressure to a clear paste with a relative density of about 1.35 (measured at 60°C), and vacuum-dry (60°C) to obtain a dry paste. Crush, sieve (through 80 mesh sieve), add appropriate amount of starch, mix well, granulate with 80% ethanol (18 mesh sieve), dry (60°C), granulate (18 mesh sieve), add appropriate amount of microcrystalline Cellulose and 0.1% magnesium stearate, compressed into 1000 tablets, that is.

Embodiment 2

[0159] Embodiment 2, sugar-coated tablet of the present invention

[0160] 300 parts of psoralen, 480 parts of motherwort, 300 parts of desmodium

[0161] 300 parts of Haijinsha, 30 parts of amber, 240 parts of Shanzi mushroom

[0162] Weigh the six herbs, crush the amber into fine powder, pass through an 80-mesh sieve, and set aside; the rest of the five flavors such as psoralen, among which sea ginseng is fried, add 8 times the amount of water each time and cook twice, the first time for 3 hours, The second time is 1 hour; the decoction is combined, filtered, and the filtrate is concentrated under reduced pressure to a clear paste with a relative density of about 1.35 (measured at 60° C.), vacuum dried (60° C.) to obtain a dry paste. Pulverize, sieve (through 80 mesh sieve), add the amber fine powder and appropriate amount of starch, mix well, granulate (18 mesh sieve) with 80% ethanol, dry (60°C), granulate (18 mesh sieve) , add an appropriate amount of microcrystalline c...

Embodiment 3-7

[0164] The kind of medicinal material of embodiment 3-5 and preparation are the same as embodiment 1, the kind of medicinal material of embodiment 6-7 and preparation are the same as embodiment 2

[0165] Table 10 Examples 3-7

[0166]

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PUM

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Abstract

The invention discloses a medicament for curing dysuria, a preparation method and a quality control method thereof. The medicament is prepared by mainly using the following raw materials in part by weight: 240 to 360 parts of semen psoraleae, 360 to 560 parts of leonurus, 240 to 360 parts of spora lygodii and 180 to 300 parts of tulip bulb. In the quality control method, a plurality of medicinal materials in the product are controlled by an HPLD method and a TLC method. The medicament, the preparation method and the quality control method thereof have the advantage that: a clinical experiment shows that the effective rate of an experimental group is 98.85 percent and the effective rate of a control group is 96.92 percent. Due to dried powder directly used as medicament, the best concentration proportion and a specific drying condition, the process can be controlled better compared with the process of using clear paste as medicament.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and relates to a medicine for treating dysentery, a preparation method of the medicine, and a quality control method. Background technique [0002] Prostatic hyperplasia, also known as prostatic hypertrophy, is a common disease that affects the health of elderly men due to the obvious enlargement of the prostate gland. Prostatic hyperplasia is clinically characterized by progressive frequent urination and dysuria. Benign prostatic hyperplasia belongs to the category of "infirmity" and "infirmity" in traditional Chinese medicine. Insufficiency refers to the small amount of urination, drips come out, and even the urination is blocked. Among them, the urination is difficult, the drip is short, and the disease is relatively slow. "close". [0003] In recent years, the average life expectancy of my country's population is increasing, there are more and more elderly people, and the incide...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P13/08G01N30/02G01N30/90A61K35/10
Inventor 佟雪松
Owner 秦皇岛润青制药有限公司
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