Preparation method and quality control method of traditional Chinese medicine preparation for treating bronchitis and bronchial asthma

A technology for bronchial asthma and bronchitis, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, measuring devices, etc., can solve problems such as difficult radical cure, hormone dependence of patients, and increased asthma mortality, and achieves reduction of processes and turnover, and The effect of high bioavailability and shortened production cycle

Active Publication Date: 2010-09-15
SHANDONG MINGREN FURUIDA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The pathogenesis of asthma is complicated, the onset is acute, the onset is fast, and often protracted, difficult to cure, and there is no effective treatment method at present
Western medicine mostly uses anti-inflammatory adrenal cortex hormone, combined with β 2 Receptor stimulants, anticholinergic drugs, theophylline drugs, etc., but long-term use of these drugs can bring side effects such as hormone dependence, obesity, and endocrine disorders to patients. The increased rate may be related to the toxic effects of theophylline, side effects of bronchodilator aerosols, and "bounce syndrome" of sympathomimetics

Method used

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  • Preparation method and quality control method of traditional Chinese medicine preparation for treating bronchitis and bronchial asthma
  • Preparation method and quality control method of traditional Chinese medicine preparation for treating bronchitis and bronchial asthma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Take the ten herbs in the original prescription, take Poria cocos (1 / 2 prescription amount), and grind them into fine powder; Ginkgo and bitter almonds are ground into the coarsest powder, and decoct the remaining seven flavors such as Poria cocos and earthworm for three times. The first and second times are 2 hours each, and the third time is 1 hour. Add 10 times the amount of water each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.16-1.18 (50°C). Add Poria cocos Fine powder, mixed, that is, the extraction extract.

Embodiment 2

[0032] Take the ten herbs in the original prescription, take 1 / 2 prescription amount of Poria cocos, and crush them into fine powder; Ginkgo and bitter almonds are crushed into the coarsest powder, and decoct with the remaining seven flavors such as Poria cocos and earthworm for three times. The second time is 2 hours each, and the third time is 1 hour. The amount of water added is 10 times, 8 times, and 8 times respectively. The decoction is combined and filtered. paste, add Poria cocos fine powder and mix well to get the extract.

Embodiment 3

[0034] Add 80g of dextrin to any one of the above-mentioned extracts, mix evenly, and granulate in one step, add 3.5g sodium lauryl sulfate to the obtained granules, mix evenly, and pack into capsules, which is the capsule of the present invention agent.

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Abstract

The invention discloses a preparation method and a quality control method of a traditional Chinese medicine preparation for treating bronchial asthma, chronic asthmatic bronchitis, emphysema and early pulmonary heart diseases. The preparation method is characterized by being a preparation method of a cough-relieving capsule as a traditional Chinese medicine preparation formed by reforming a cough-relieving tablet, optimization and screening are carried out on an extraction process, and modern new equipment and new method are adopted so as to be suitable for large-scale industrial production; the research on the quality standard is to perfect and improve on the basis of the original standard to establish a perfect method for thin bed identification and content determination so that the quality standard of a product is advanced and controllable, and the clinical effect is ensured.

Description

1. Technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and relates to a preparation method and a quality control method of a traditional Chinese medicine preparation for treating bronchial asthma, asthmatic bronchitis, emphysema and early pulmonary heart disease. 2. Background technology [0002] Bronchial asthma is a common complicated clinical syndrome of respiratory infectious inflammation and allergic inflammation. Shoulder lifting, chest buzzing, forehead sweating, difficulty lying down, repeated attacks, each lasting for a few minutes, hours or even days, often at night and early in the morning; when the attack is severe, it can cause heart and lung failure and endanger life. The morbidity rate varies from 1% to 13% in various countries in the world, and the morbidity rate and mortality rate are still increasing. The number of patients who die from asthma is as high as 180,000 in the world every year. The prevalence...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/48A61P11/06A61P11/14A61P11/00A61P9/00G01N30/02G01N30/90A61K35/64A61K35/62
Inventor 张玲凌沛学刘妍妍
Owner SHANDONG MINGREN FURUIDA PHARMA
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