Ultrasonic and nuclear magnetic resonance image fusion transluminal registration device and method

Abstract

The invention relates to an ultrasonic and nuclear magnetic resonance image fusion transluminal registration device, which is provided with a carrier, a support, a regulating device and a base, wherein the carrier is arranged on the support; the support is connected with the base through the regulating device; and markers arranged in the carrier. The invention also provides an ultrasonic and nuclear magnetic resonance image fusion transluminal registration method. The invention has the advantages that: the device and the method are simple, convenient, accurate and quick in prostate transrectal ultrasonic and nuclear magnetic resonance image registration, and only needs to register layers, which have the same number of target markers, in two modes; the device and the method avoid injuring patients and avoids implanting the markers in the bodies of the patients and injuries and use limitation thus caused; and the volume of the device is small, the diameter of the device is equal to thatof a transrectal ultrasonic probe, and the tolerance and acceptability of the patients are high.

Description

technical field [0001] The invention relates to the field of image registration, in particular to an ultrasonic and nuclear magnetic resonance image fusion intracavity registration device and method thereof. Background technique [0002] In the image registration fusion of prostate magnetic resonance imaging (MRI) and transrectal ultrasound imaging (TRUS) to guide prostate biopsy, the existing image registration techniques mainly include: [0003] 1. Using radioactive particles implanted in the prostate in prostate brachytherapy as image registration markers; [0004] 2. Use the contour features and pixel features of the prostate itself, the calcification in the prostate, the internal urethral opening and other anatomical landmarks, the edge contour of the prostate and its transition zone, or the relevant lesions in the prostate as internal markers for image registration; [0005] 3. An electromagnetic tracer positioning system consisting of a magnetic field generator, an u...

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Problems solved by technology

[0007] 1. The radioactive particles implanted in the prostate for prostate brachytherapy are used as image registration markers. They must be placed before imaging through invasive techniques, which will cause varying degrees of damage to patients, and the applicable population is limited to prostate cancer patients. Patients with brachytherapy are not conducive to large-scale clinical application;

[0008] 2. To use the contour features and pixel features of the prostate, calcifications in the prostate, anatomical landmarks such as the internal opening of the urethra, the edge contours of the prostate and its transition zone, or related lesions in the prostate as internal markers for image registration, the operator needs to be aware of these In addition, due to the pressure formed by the bladder and rectum with different filling levels, the patient's position, the inner diameter of the rectal ultrasound probe and MRI rectal coil are inconsistent, and the biopsy needle during the intervention These factors will lead to different degrees of displacement and deformation of the prostate. At this time, the registration method relying on the geometric shape of the prostate and local points, lines, surfaces, and surface contour features will have a large error.

The utility model has a complex structure, and can only perform registration processing on in vitro images, and has a limited range of application, and cannot perform accurate biopsy on prostate cancer, etc.

[0011] Since transrectal ultrasonography-guided prostate biopsy and pathological diagnosis are the gold standard for clinical preoperative diagnosis of prostate cancer, there is an urgent need for a method that can be clearly identified by other imaging examinations (such as magnetic resonance imaging) without conventional ultrasonography. An image fusion and registration device for accurate biopsy of the target prostate cancer lesion, but there is no report on this device

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