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Antiviral antidiarrheal medicine for treating children with autumn viral diarrhea and spleen deficiency diarrhea

A viral diarrhea, antiviral technology, applied in antiviral agents, drug combinations, pharmaceutical formulations, etc., can solve problems such as time-consuming and drug-consuming

Inactive Publication Date: 2011-11-30
吴新治
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific anti-rotavirus drug for the treatment of this kind of viral diarrhea. Most of the treatment is to replenish water, supportive therapy, and regulate electrolyte balance. Although the curative effect is good, it is time-consuming and expensive.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] (1) Take Burnet Burnet 40g, Curcuma Curcuma 30g, Chinese Yam 50g, Fructus Rosa Fructus 18g, distilled water and preservatives in sufficient quantities according to the weight ratio of active ingredients;

[0037] (2) Use the "distillation method" to extract the active ingredient volatile oil from the zedoary, and the "water extraction" to extract the water-soluble active ingredients, specifically: cut the zedoary into 0.2-0.3mm thin slices, put it in a steam filter tank, add water and heat "Distill" the volatile oil, steam until the volatile oil comes out, collect the volatile oil for later use, take out the grid steamer, add water in an amount of about 1:5 to the weight of the raw material, heat to 60°C for 1.0 hours, boil for 0.5 hours, take the liquid as A1; The amount is 1:5, and the medicinal solution is decocted in the same way as A2. Mix and filter the medicine liquid A1 and A2, concentrate under reduced pressure and low temperature, and separate the liquid and s...

Embodiment 2

[0041] Embodiment two: (Part A)

[0042] (1) Take Burnet Burnet 36g, Curcuma Curcuma 24g, Yam 48g, Fructus Rosa 16g, Pueraria 16g, 80% concentration ethanol, distilled water and preservative according to the weight ratio of active ingredient raw materials for subsequent use;

[0043] (2) Extract volatile oil from Curcuma with "distillation method", and extract water-soluble active ingredients with "water extraction method", specific method: get thick ointment A, or medicated powder A and volatile oil A by embodiment 1 (2) for subsequent use.

[0044] (3) Extract active ingredients from Burnet elm, Chinese yam, and Fructus Rosa Radix by "water extraction method", specific method: get thick ointment B or medicinal powder B according to the item (3) of embodiment 1 for subsequent use.

[0045] (4) Use the "alcohol extraction method" to extract the active ingredients from the simmered kudzu root. The specific method: put the baked kudzu root into a steaming filter tank, add 80% co...

Embodiment 3

[0048] Embodiment three: (Party B)

[0049] (1) Weigh Burnet Burnet (stir-fried with vinegar) 32g, Zezhu 16g, Chinese yam stir-fry 10g, Rosa laevigata 16g, stewed kudzu root 12g, atractylodes 15g, stewed myrobalan 6g, stewed nutmeg 6g, 80% concentration of ethanol, distilled water and preservatives in sufficient quantities for backup;

[0050] (2) Extract volatile oil from Curcuma with "distillation method", and extract water-soluble active ingredients with "water extraction method", specific method: get thick ointment A, or medicated powder A and volatile oil A by embodiment 1 (2) for subsequent use.

[0051] (3) Use "water extraction method" to extract active ingredients of Burnet, Chinese yam, Rosa japonica, simmering Ke Zi, and Nutmeg. The specific method: according to the item (3) of Example 1, thick ointment B or medicinal powder B is obtained for subsequent use.

[0052] (4) Extract the active ingredient by "alcoholic extraction" of Pueraria radiata stew, specific meth...

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PUM

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Abstract

The invention discloses an antiviral, invigorating spleen and antidiarrheal drug for treating children with autumn viral diarrhea and spleen-deficiency indigestion diarrhea and a preparation method of the drug. Active ingredients, and then add pharmaceutically acceptable carriers or excipients made of oral preparations. The medicine and the preparation method of the present invention are unique, can resist virus, anti-inflammation and antipyretic, relieve nausea and vomiting, inhibit intestinal propulsion function, improve intestinal microcirculation, promote the regeneration of epithelial cells damaged by small intestinal mucosal endothelium, accelerate the repair of intestinal mucosa, and invigorate the spleen Nourishing the stomach, promoting body fluid and astringent intestines to relieve diarrhea. It has been used in clinical trials to treat children with autumn viral diarrhea and has achieved good curative effect. It can also treat children with spleen-deficiency diarrhea and dyspepsia diarrhea with intestinal hyperactivity, and has no toxic side effects on the human body and internal organs.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an antiviral and antidiarrheal medicine for treating children with autumnal viral diarrhea and indigestion due to spleen deficiency and a preparation method thereof. Background technique [0002] Autumn viral diarrhea in children is a gastrointestinal disease caused by rotavirus infection that causes fever, vomiting and diarrhea. It occurs every year in autumn and winter. Children aged 6 months to 2 years are susceptible to this rotavirus infection, leading to inflammation of the gastrointestinal tract, resulting in fever, Vomiting, diarrhea. This kind of viral diarrhea only infects children and occurs in autumn, so it is called autumn viral diarrhea in children. Seriously affect children's health. At present, there is no specific anti-rotavirus drug to treat this kind of viral diarrhea. Most of the treatments are water replenishment, supportive therapy, and electro...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/12A61P1/14A61P31/12
Inventor 吴新治
Owner 吴新治
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