Traditional Chinese medicine composition for treating constipation, as well as preparation method and application thereof

A technology for treating constipation and a composition is applied in the field of traditional Chinese medicine compositions and preparations for treating constipation, which can solve the problems of treating the symptoms but not the root cause, unstable curative effect, low cure rate and the like, and achieves the effects of no toxic and side effects, strict compatibility and definite curative effect.

Active Publication Date: 2013-01-16
HUBEI NUOKETE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses "Dachengqi Decoction", rhubarb, senna, magnesium sulfate, etc. to laxative stools, which are still dry after relapse; Western medicine mostly uses "Fructose" to laxative, or " "Kaisaitong" relieves the disease, but it has the disadvantages of treating the symptoms but not the root cause, the curative effect is unstable, the cure rate is low, generally 20%, and it is easy to relapse

Method used

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  • Traditional Chinese medicine composition for treating constipation, as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating constipation, as well as preparation method and application thereof
  • Traditional Chinese medicine composition for treating constipation, as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0027] Example 1: Take 18g of Radix Astragali, 65g of Atractylodes Rhizoma Atractylodes Rhizome, 18g of pig gall powder, 12g of Citrus aurantii, 8g of tangerine peel, 17g of Yu Liren, 10g of aster, 14g of Chuanxiong, and 18g of Guya. 10 times the weight, decoct for 1.5 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoction, 0.07MPa, 60-70 ℃ reduced pressure concentration to 65 ℃ when the relative density is 1.15 extract, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure at 0.07MPa and 65°C to At 65°C, the relative density is 1.25, and the ethanol is recovered to obtain a concentrated solution, which is then spray-dried (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 85°C, the material temperature is 80°C, and the atomization pressure is 0.2 Mg Pa, spray speed ...

Embodiment 2

[0028] Example 2: Take 20g of Astragalus membranaceus, 60g of Atractylodes macrocephala, 20g of pig gall powder, 10g of Citrus aurantii, 10g of tangerine peel, 15g of Yu Liren, 12g of aster, 12g of Chuanxiong, and 20g of Guya. 8 times the weight, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal materials, decoct for 1 hour, combine the decoction, 0.07MPa, 60-70 ℃ reduced pressure concentration to 65 ℃ when the relative density is 1.20, Add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate under reduced pressure at 0.07MPa and 65°C to the relative density at 65°C It is 1.30, and the ethanol is recovered to obtain a concentrated solution, which is filtered, added with water and sucrose to prepare an oral solution.

Embodiment 3

[0029] Example 3: Take 22g of Radix Astragali, 55g of Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome, 22g of pig gall powder, 8g of Fructus Citrifolia, 12g of Tangerine Peel, 13g of Yu Liren, 14g of Aster, 10g of Rhizoma Chuanxiong, and 22g of Guya. 12 times the weight, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal materials, decoct for 2 hours, combine the decoction, 0.07MPa, 60-70 ℃ reduced pressure concentration to 65 ℃, the relative density is 1.20 For the extract, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, let stand for 24 hours, filter, and concentrate the filtrate to 65°C under reduced pressure at 0.07MPa and 65°C When the relative density is 1.30, and ethanol is reclaimed, the concentrated solution is obtained, and the concentrated solution is spray-dried (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 90°C, the material temperature is 90°C, a...

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Abstract

The invention provides a traditional Chinese medicine composition for treating constipation, as well as a preparation method and application thereof. The traditional Chinese medicine composition mainly comprises the following Chinese herbal medicines in parts by weight: 18-22 parts of astragalus root, 55-65 parts of rhizoma atractylodis macrocephalae, 18-22 parts of pulvis fellis suis, 8-12 partsof fructus aurantii, 8-12 parts of dried tangerine peel, 13-17 parts of bunge cherry seed, 10-14 parts of tatarian aster root, 10-14 parts of rhizoma chuanxiong and 18-22 parts of rice-grain sprout. The traditional Chinese medicine composition can be prepared into oral liquid, tablets, capsules or granules by a corresponding preparation method. The traditional Chinese medicine composition has functions of tonifying middle-Jiao and qi and invigorating spleen for assisting spleen transportation and transformation, thus achieving the purpose of treating constipation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating constipation, a preparation method and application thereof. Background technique [0002] Constipation is a common disease. The main clinical manifestation is long-term dry stool. It is difficult and painful to defecate every time, and it is easy to cause other diseases for a long time. The cause of the disease, according to the comprehensive analysis of traditional Chinese medicine, is due to overeating, hot and delicious food, excessive drinking, resulting in accumulated heat in the stomach, or after typhoid fever, residual heat lingers and insufficient body fluid, resulting in dry and hot intestines; due to emotional discomfort, reduced exercise , stagnation of qi, abnormal circulation, dereliction of duty in conduction; due to fatigue and internal injury, after illness, postpartum women or the elder...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P1/10A61K35/413
Inventor 石振拓
Owner HUBEI NUOKETE PHARMA
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