Method for preparing relaxing and face-cleansing cosmetics and application

A cosmetic and soothing technology is applied in the field of preparation of soothing and calming cosmetics, which can solve the problems of less efficacy and inconspicuous effects, and achieve the effects of strong transdermal absorption, strengthening cell metabolism, and preventing the spread of inflammation.

Active Publication Date: 2012-03-21
广州泰润合投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are all kinds of beauty cosmetics on the market for sensitive skin, but most of the functional ingredients used are anti-inflammatory or anti-irritant chemical agents or plant extracts, most of these functional ingredients are only functional. To resist irritation, eliminate inflammation, and protect cells, that is, the first layer of sensitive skin mentioned above, it has less effect on the second layer, even if it has an effect, it is not obvious

Method used

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  • Method for preparing relaxing and face-cleansing cosmetics and application
  • Method for preparing relaxing and face-cleansing cosmetics and application
  • Method for preparing relaxing and face-cleansing cosmetics and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of soothing and calming lyophilized powder:

[0026] Weigh 0.3g IL-1RA, 0.3gKGF-2, 43g low-molecular-weight heparin sodium, 1050g stabilizer, add 20000ml injection grade water, filter and sterilize, fill in 2.1ml / bottle, and vacuum freeze-dry for 20-35h.

[0027] Wherein the stabilizer formula is: glycerol with a concentration of about 3wt%, mannitol and water with a concentration of about 4wt%, vitamin D with a concentration of about 1wt%, and sodium carbonate with a concentration of about 5mM.

[0028] Preparation of Soothing and Serene Essential Liquid:

[0029] Basic liquid formula: (wt%)

[0030] Hyaluronic Acid 0.15

[0031] Sodium Vitamin C Phosphate 0.2

[0032] 1,2 hexanediol 0.3

[0033] Lactobacillus / mung bean fermentation broth 0.6

[0034]Lysoprotease 1.0

[0035] The balance is water

[0036] After the above formula is weighed and dissolved in proportion, it is filtered and sterilized, filled at 3ml / bottle, crimped and sealed.

[0037] ...

Embodiment 2

[0039] Preparation of soothing and calming lyophilized powder:

[0040] Weigh 0.4g IL-1RA, 0.4gKGF-2, 43g low-molecular-weight heparin sodium, 1100g stabilizer, add 20000ml injection grade water, filter and sterilize, fill in 2.1ml / bottle, and vacuum freeze-dry for 20-35h.

[0041] The stabilizer formula is: polyvinylpyrrolidone with a concentration of about 1.5wt%, mannitol and water with a concentration of about 4wt%, sodium thiosulfate with a concentration of about 1wt%, and amino acid with a concentration of about 7mM.

[0042] Preparation of Soothing and Serene Essential Liquid:

[0043] Basic liquid formula: (wt%)

[0044] Hyaluronic Acid 0.15

[0045] Sodium Vitamin C Phosphate 0.2

[0046] Methylpropanediol 2.0

[0047] Lactobacillus / mung bean fermentation liquid 0.6

[0048] Lysoprotease 1.0

[0049] The balance is water

[0050] After the above formula is weighed and dissolved in proportion, it is filtered and sterilized, filled at 3ml / bottle, crimped and seal...

Embodiment 3

[0053] Preparation of soothing and calming lyophilized powder:

[0054] Weigh 0.5g IL-1RA, 0.5gKGF-2, 40g low-molecular-weight heparin sodium, 1200g stabilizer, add 20000ml injection grade water, filter and sterilize, fill in 2.1ml / bottle, and vacuum freeze-dry for 25-40h.

[0055] The stabilizer formula is: trehalose with a concentration of about 2.5wt%, lactose with a concentration of about 5.0wt%, vitamin D with a concentration of about 1.5wt%, and sodium carbonate with a concentration of about 8mM.

[0056] Preparation of Soothing and Serene Essential Liquid:

[0057] Basic liquid formula: (wt%)

[0058] Hyaluronic Acid 0.15

[0059] Sodium Vitamin C Phosphate 0.2

[0060] 1,2 hexanediol 0.35

[0061] Lactobacillus / mung bean fermentation liquid 0.6

[0062] Methylpropanediol 4.0

[0063] The balance is water

[0064] After the above formula is weighed and dissolved in proportion, it is filtered and sterilized, filled at 3ml / bottle, crimped and sealed.

[0065] Whe...

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PUM

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Abstract

The invention relates to a method for preparing relaxing and face-cleansing cosmetics and application. The cosmetics comprises the following components in percentage by mass: 0.00001 to 0.001 percent of recombinant human keratinocyte growth factors, 0.00001 to 0.001 percent of recombinant human interleukin-1 receptor antagonist, 0.1 to 0.5 percent of low-molecular sodium heparin, 5 to 25 percent of stabilizer, 0.02 to 0.3 percent of hyaluronic acid, 0.5 to 8 percent of vitamin C sodium phosphate, 0.5 to 5 percent of methyl propanediol, 0.3 to 0.7 percent of 1,2 hexanediol, 0.5 to 3.5 percent of lactobacillus / mung bean fermentation liquor, 0.5 to 5 percent of dissolved protease and the balance of water. The relaxing and face-cleansing cosmetics are applied to sensitive skin, can be stored for a long time, and is suitable for long-term use.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a preparation method and application of soothing and calming cosmetics. Background technique [0002] Sensitive skin is skin that is easily irritated causing some degree of discomfort. When the external environment changes, the skin cannot adjust, resulting in discomfort and allergies. Sensitive skin is easy to cause skin surface dryness, redness, red blood streaks, spots, eye swelling, peeling or acne due to diet, emotions or skin care products used. As the living environment deteriorates, the allergens around us are also increasing, and the extensive use of cosmetics and chemical agents makes our skin more fragile and sensitive, so the number of people with sensitive skin is gradually increasing. The treatment and prevention of sensitive skin has the following two levels: 1. Eliminate inflammatory factors, inhibit and resist the secretion and aggregation of skin allergic substances: ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/73A61K8/64A61Q19/00A61P17/00A61P17/10A61P29/00A61P37/08
Inventor 罗丽华万宇陈凡
Owner 广州泰润合投资有限公司
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