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Production process for extracting L-serine from reeling waste silk

A production process and technology of serine, which is applied in the field of production process of extracting L-serine from reeling bottom toes, can solve the problems of high cost, high cost, troublesome post-processing, etc., achieve good economic and social benefits, and improve product quality. Added value, easy operation control effect

Inactive Publication Date: 2012-05-02
杨永前
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Problems solved by technology

Its preparation method mainly includes chemical synthesis method. The biggest advantage of chemical synthesis method is that it can use a variety of chemical raw materials, a variety of process routes, large production scale, and easy separation and purification of products. However, the biggest disadvantage of this method is: the cost of raw materials used is relatively high , high toxicity; fermentation method, using glycine and glyceric acid as precursor fermentation to produce L-serine, but this method has high requirements for equipment, generally low acid production rate, difficult separation, troublesome post-processing, and low extraction rate, so High cost and expensive; enzymatic method, although enzymatic production has the characteristics of simple process, short cycle, low energy consumption, strong specificity and high yield, but the current technology is not mature enough to apply them to industrial production There are also reports of directly extracting L-serine from silkworm cocoons. The content of serine in cocoon cocoons is about 14%. However, due to the high cost of silkworm cocoons, reaching 35-45 yuan / kg, the cost is high.

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  • Production process for extracting L-serine from reeling waste silk
  • Production process for extracting L-serine from reeling waste silk

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Embodiment Construction

[0017] Below in conjunction with accompanying drawing and embodiment, the present invention is described in further detail, but does not constitute any restriction to the present invention:

[0018] according to figure 1 , a kind of production technique that extracts L-serine from reeling waste silk, it is characterized in that, described production technique comprises the following steps:

[0019] 1. Acid hydrolysis. Add 30kg of silk reeling waste and 150L of hydrochloric acid with a concentration of 6mol / L into the hydrolysis tank, stir and heat for 110°C for 16-20h, cool to below 40°C, and filter to obtain the filtrate. Wash with water, and the washing solution is combined into the filtrate to obtain about 800 L of hydrolyzate.

[0020] 2. Deacidification and dehydration. The hydrolyzate in step 1 was processed from top to bottom at a flow rate of 110mL / min into H + Type 732 cation exchange resin column, and then wash the pigment with pure water until there is no Cl - ...

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Abstract

The invention discloses a production process for extracting L-serine from reeling waste silk. The production process comprises the steps of acid hydrolysis, deacidification, elution, fractionation, concentration, crystallization and refining. The production process has the advantages of simplicity, easiness in operation and control, and good economical benefit and social benefit; moreover, production cost is reduced, an additional value of a product is improved, and pollution is avoided.

Description

Technical field: [0001] The invention relates to a production process of L-serine, in particular to a production process of extracting L-serine from silk reeling waste. Background technique: [0002] L-serine is a non-essential amino acid and has many important physiological functions and effects. Therefore, it is widely used in medicine, food and cosmetics. Its preparation method mainly includes chemical synthesis method. The biggest advantage of chemical synthesis method is that it can use a variety of chemical raw materials, a variety of process routes, large production scale, and easy separation and purification of products. However, the biggest disadvantage of this method is: the cost of raw materials used is relatively high , high toxicity; fermentation method, using glycine and glyceric acid as precursor fermentation to produce L-serine, but this method has high requirements for equipment, generally low acid production rate, difficult separation, troublesome post-proc...

Claims

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Application Information

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IPC IPC(8): C07C229/22C07C227/40
Inventor 杨永前王福根史东来
Owner 杨永前
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