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Traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome as well as preparation method and application thereof

A technology for irritable bowel syndrome and traditional Chinese medicine pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc. The effect of reducing the number of black stools, avoiding side effects, and prolonging the incubation period

Active Publication Date: 2012-07-18
SHAANXI MOMENTUM QIXUEHE PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Acute and chronic gastroenteritis and irritable bowel syndrome are common and frequently-occurring diseases. At present, antibiotics are the main treatment for such diseases. However, antibiotics often have certain toxic and side effects, and long-term use can cause intestinal The flora is disturbed and prone to drug resistance
Changyanning syrup, a traditional Chinese medicine, has poor stability and is inconvenient to carry and transport. It is taboo for diabetics

Method used

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  • Traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome as well as preparation method and application thereof
  • Traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome as well as preparation method and application thereof
  • Traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 pill preparation (changyanning pill)

[0027] formula:

[0028] Dijin grass 4583.3g Yellow hair ear grass 6250g Camphor root 4583.3g

[0029] Cranberries 2291.7g Maple leaves 2291.7g

[0030] Preparation method: decoct the above five flavors twice with water, add 10 times the amount of water each time, decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a clear liquid with a relative density of about 1.20 (80°C). Paste, add 2438ml of 95% ethanol, stir, let stand for 12 hours, filter, the filtrate is concentrated under reduced pressure at 80°C to a clear paste with a relative density of about 1.25 (80°C), add 249g of starch, mix well, and refine honey: water (1:1) was made into pellets for the binder, dried at 60°C, and polished. Pack into bags, pack, and make 1000g in total.

Embodiment 2

[0032] formula:

[0033] Dijin grass 4590g Yellow hair ear grass 6250g Camphor tree root 4590g

[0034] Herbs 2285g Maple leaves 2285g

[0035] Preparation method: decoct the above five flavors twice with water, add 10 times the amount of water each time, decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure at 80°C to a clear liquid with a relative density of about 1.20 (80°C). Paste, add 2438ml of 95% ethanol, stir, stand for 12 hours, filter, the filtrate is concentrated under reduced pressure at 80°C to a clear paste with a relative density of about 1.25 (80°C), add 249g of starch, mix well, and refine honey: Water (1:1) was used as the binder to make pellets, dried at 60°C, and polished. Make 1000g altogether, bag, pack and get final product.

[0036] Instantly.

Embodiment 3

[0038] The preparation process parameter research experiment of the present invention:

[0039] 1. Extraction experiments with different water additions:

[0040] Weigh 687.50g of Dijincao, 937.5g of Pleurotus chinensis, 687.50g of camphor tree root, 343.75g of fennel, 343.75g of maple leaves, a total of 3000g, a total of 5 parts, add different amounts of water respectively, and decoct according to the basic extraction process , The decoction is concentrated under reduced pressure to a thick paste, dried under reduced pressure at 60-70°C, weighed, and the paste yield is calculated, and the amount of water added is determined according to the change of the paste yield. The results are shown in Table 1:

[0041] Table 1 Extraction test with different water additions

[0042] test

[0043] The above results show that in order to reduce energy consumption in large-scale production, it is more reasonable to set the amount of water added at 10 times.

[0044] 2. Study o...

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Abstract

The invention provides a traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome. The traditional Chinese medicine pill is prepared from the following traditional Chinese medicine raw materials in parts by weight: 3500-5500 parts of creeping euphorbia, 5500-7000 parts of goldhair hedyotis herb, 3500-5500 parts of camphor tree roots, 1500-3000 parts of elsholtzia and 1500-3000 parts of maple leaves. The prepared traditional Chinese medicine pill is subjected to a mouse diarrhea relieving observation experiment, the result shows that the delitescence of defecating melena of the mouse is obviously prolonged and the melena quantity is reduced; a mouse small intestine ink propulsion test shows that the small intestine peristalsis of the mouse is reduced; 286 cases of patients with acute gastroenteritis, including 146 cases of male and 140 cases of female, are selected for clinical observation experiment, the result shows that the cure rate of the patients is obviously improved and the total effective rate is 99%; and 76 cases of patients with irritable bowel syndrome take a curative effect observation test, and the total effective rate reaches 97%. The traditional Chinese medicine pill is reasonable in formula, stable in quality, good in safety and convenient for storage, carrying and use; the side effect caused by taking antibiotics is avoided, and the clinical application value is high; and the method is suitable for industrial production.

Description

technical field [0001] The invention relates to traditional Chinese medicines, in particular to traditional Chinese medicine pills, in particular to a traditional Chinese medicine pill for treating gastroenteritis and irritable bowel syndrome, as well as its preparation method and application. Background technique [0002] Acute gastroenteritis is a common and frequently-occurring disease in summer and autumn. It is mostly caused by microbial infection such as bacteria and viruses, and its main manifestations are abdominal pain, diarrhea, nausea, vomiting, fever, etc., and severe cases can cause dehydration, electrolyte imbalance, shock, etc. Most patients manifest as nausea and vomiting first, followed by diarrhea, ranging from 3 to 5 times a day, or even several 10 times. The stool is watery, dark yellow or greenish, and has a foul smell. Symptoms such as soreness. The incidence of acute enteritis (1) bacterial and toxin infection: mainly Salmonella, halophilic bacteria ...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61K9/20A61P1/00
Inventor 王保安毛鹏
Owner SHAANXI MOMENTUM QIXUEHE PHARMACEUTICAL CO LTD