Manufacturing method of glucose

Abstract

The invention discloses a manufacturing method of glucose, comprising the following steps of: (1) liquefying starch: by taking starch as the raw material, liquefying under the action of a liquefying enzyme after size mixing, and then, a glucose saccharified liquid under the action of a saccharifying enzyme; (2) filtering and decontaminating the saccharified liquid by a membrane filtering unit to obtain filtrate, wherein a filtering membrane has the aperture of 1-200nm or the molecular weight cut-off of 10-500kd; (3) carrying out continuous ion exchange on the filtrate by using a moving bed, removing salts to obtain a purified liquid; and (4) filtering the purified liquid by using a nanofiltering membrane to obtain pharmaceutical-grade glucose, wherein a concentrated solution is used for producing daily chemical alcohol or polysaccharose products. Continuous production is adopted in the manufacturing method, and therefore, the production efficiency is high.

Description

technical field [0001] The invention relates to the field of biochemistry, in particular to a method for producing glucose. Background technique [0002] Glucose is an important monosaccharide and an important basic chemical medicine, as well as a raw material for many compounds. The production of glucose has experienced the development process of acid method, acid enzyme method and double enzyme method. see figure 1 , the existing production process for producing glucose is as follows: use starch as raw material, liquefy under the action of liquefying enzyme after pulping, then saccharify through the action of glucoamylase, finally form glucose syrup with DX95%, and then use diatom Soil filtration method enters plate frame or drum for filtration to remove residual starch and suspended matter, then adopts fixed bed ion exchange process, mainly uses a large amount of anion and cation exchange resin to remove the salt in the sugar solution, and finally uses heavy The crysta...

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Problems solved by technology

[0003] This production process has the following disadvantages: 1. During the plate-frame or drum filtration process, diatomite and filter residue are continuously discharged and cannot be recycled, and impurities such as protein and fat in the sugar solution cannot be removed well, and the impurities will be Entering the follow-up ion exchange process will bring pollution to the resin and reduce the service life of the resin; second, the regeneration of the resin needs to consume a large amount of acid-base and water, and will produce a large amount of acid-base wastewater, which is seriously polluted; third, the main end product of glucose is fruit Glucose syrup, crystalline glucose and pharmaceutical grade glucose, in order to meet the high purity requirements of pharmaceutical grade glucose, the traditional process can only use recrystallization to improve the purity, so a large number of crystallizers and centrifuges are required, which requires a large investment and land occupation, and requires A large number of operators, low work efficiency and low process yield; 4. On the whole, the traditional production process is a batch operation with a low degree of automation, requiring a lot of manpower, and the product quality and yield are relatively low

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