The object of the present invention is to provide a closed powder box for powder supply center, including: powder catcher, powder box cover plate, cylinder, powder box body, vibrating assembly, powder return port, powder filling port, pump seat, guide assembly , control device, powder supply center body and vibration motor, characterized in that: the vibration assembly is arranged in the powder supply center body, the vibration motor is installed at the lower end of the vibration assembly, and the vibration motor and the vibration assembly are connected to each other. The powder box body is arranged on the upper end of the vibrating assembly. The beneficial effect of the present invention is that: the present invention has combined the advantage of open type powder box and old-fashioned airtight powder box, keeps powder box airtight when spraying, does not overflow powder, can directly replace powder box casing when cleaning and changing colors, avoids It solves the problem of color mixing caused by unclean cleaning during color change, which can not only improve the working environment, but also shorten the color change time, improve production efficiency and reduce the work intensity of operators.