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External medicament for treating vulvar dystrophy

A vulvar dystrophy and topical drug technology, applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of high recurrence rate and poor clinical curative effect, and achieve lesion tissue repair, significant clinical curative effect, Improve the effect of the local environment

Active Publication Date: 2013-12-11
SHANXI PROVINCE CHINESE MEDICINE RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The treatment of vulvar dystrophy by Western medicine is mainly based on topical medication, including hormone therapy, chemotherapy drug therapy, SOD compound enzyme therapy, local physical therapy and surgical resection of diseased tissue, but the clinical efficacy is poor and the recurrence rate is high

Method used

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  • External medicament for treating vulvar dystrophy
  • External medicament for treating vulvar dystrophy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Crush 180g of Angelica sinensis and 125g of Puhuang into fine powder for later use.

[0057] Take 375g of dodder, 250g of Puhuang, 375g of mugwort leaves, 225g of safflower, 195g of angelica, 375g of red peony, 750g of purslane, 150g of licorice, add 25Kg of water, and decoct for 1.5h. Repeat the above steps twice, combine the decoction, filter, concentrate the filtrate into a clear paste with a relative density of 1.20 (80°C), add the above-mentioned angelica and puhuang fine powder, mix well, and after drying, add 150g of borax and dried blood 75g, verdigris 75g, pulverize, make powder.

Embodiment 2

[0059] Crush 130g of Angelica sinensis and 115g of Puhuang into fine powder for later use.

[0060] Take 350g of dodder, 230g of Puhuang, 350g of mugwort leaves, 175g of safflower, 130g of angelica, 265g of red peony, 800g of purslane, 200g of licorice, add 22Kg of water, and decoct for 1.5h. Repeat the above steps twice, combine the decoction, filter, concentrate the filtrate into a clear paste with a relative density of 1.30 (60°C), add the above-mentioned angelica and puhuang fine powder, mix well, after drying, add 280g of borax, dried blood 80g, verdigris 60g, pulverize, make powder.

Embodiment 3

[0062] Crush 200g of Angelica sinensis and 85g of Puhuang into fine powder for later use.

[0063] Take 260g of dodder, 170g of Puhuang, 220g of mugwort leaves, 250g of safflower, 200g of angelica, 300g of red peony root, 600g of purslane, 300g of licorice, add 20Kg of water, and decoct for 1.5h. Repeat the above steps twice, combine the decoction, filter, concentrate the filtrate into a clear paste with a relative density of 1.32 (85°C), add the above-mentioned angelica and puhuang fine powder, mix well, after drying, add 200g of borax, dried blood 55g, verdigris 80g, pulverize, make powder.

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Abstract

The invention discloses an external medicament for treating vulvar dystrophy, and the external medicament is powder prepared by using Chinese dodder seed, cattail pollen, folium artemisiae argyi, safflower, Chinese angelica, red peony root, dragon's blood, verdigris, portulaca oleracea, borax and liquorice as bulk pharmaceutical chemicals. The using method of the external medicament comprises the following steps: dissolving the powder with hot water and performing a hip bath. The medicament has the functions of tonifying kidney and activating blood circulation, removing putrefaction and promoting tissue regeneration, and clearing heat and promoting diuresis, can be used for solving itch of a symptom and effectively improving the local environment; by virtue of external skin soaking, the skin hydration can be increased, and medicament absorption and local normal metabolic activity are promoted; and the curative effect is enhanced when the medicament is infiltrated into deep layer of skin, excessive expression of EGFR (epidermal growth factor receptor) and Ki-67 can be inhibited, and the subjective symptom of a patient can be eliminated or relieved, so that a pathological tissue can be repaired. Clinical medicine effect tests indicate that the curing and remarkably effective rate is 76.65 percent, and the total effective rate is 90.36 percent.

Description

technical field [0001] The invention relates to a medicine for treating vulvar dystrophy, in particular to an externally used medicine for treating vulvar dystrophy prepared by using traditional Chinese medicine as a raw material medicine. Background technique [0002] Vulvar dystrophy is a chronic disease characterized by degeneration and pigmentation of female vulva skin and mucous membrane tissue. It is characterized by vulvar itching and depigmentation. Cancer, the rate of malignant transformation is 3-5%, which seriously affects the physical and mental health of women, and is a chronic and difficult disease in gynecology. [0003] In 1987, the International Society for the Study of Vulvar Diseases and the International Society of Pathologists discussed and suggested that vulvar dystrophy should be divided into three types: squamous epithelial cell hyperplasia (squamo ushyperplasia, SH), lichen sclerosus (LS) and mixed type. Clinically, SH manifests as severe itching, t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61K36/896A61P15/00A61P17/04
Inventor 张晋峰
Owner SHANXI PROVINCE CHINESE MEDICINE RES INST
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