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High-efficiency calcium supplement capsule and preparation method thereof

A capsule and high-efficiency technology, applied in food preparation, capsule delivery, medical preparations containing active ingredients, etc., can solve the problems of not taking into account joint pain relief, increasing bone density effect, insufficient calcium absorption rate, etc., to relieve joint pain. , Increase bone strength, promote the effect of articular cartilage repair

Inactive Publication Date: 2012-12-05
SHANDONG CENT FOR DISEASE CONTROL & PREVENTION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a high-efficiency calcium supplement capsule and a preparation method for the deficiencies of the existing common calcium supplement preparations, such as insufficient calcium absorption rate, poor effect of increasing bone density, and inability to relieve joint pain.

Method used

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  • High-efficiency calcium supplement capsule and preparation method thereof
  • High-efficiency calcium supplement capsule and preparation method thereof
  • High-efficiency calcium supplement capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Example 1: A high-efficiency calcium supplement capsule and its preparation method

[0057] High-efficiency calcium supplement capsule formula, based on 10,000 capsules, produced in 3 batches:

[0058]

[0059] Preparation method, the steps are as follows:

[0060] (1) Pass D-glucosamine hydrochloride, chondroitin sulfate, calcium carbonate, calcium citrate malate, casein phosphopeptide, and vitamin C through an 80-mesh sieve for later use.

[0061] (2) Accurately weigh D-glucosamine hydrochloride, chondroitin sulfate, calcium carbonate, calcium citrate malate, casein phosphopeptide, and vitamin C according to the formula, and perform total mixing for 30 minutes.

[0062] (3) Fill the mixture into empty capsules.

[0063] Take the No. 0 empty capsule according to the formula, and test the car before filling, and check the difference in the filling capacity of the capsule and the disintegration time limit. The specified content of the content is 0.45g / capsule, the ...

Embodiment 2

[0065] High-efficiency calcium supplement capsule formula, based on 10,000 capsules, produced in 3 batches:

[0066]

[0067]

[0068] The preparation method is the same as in Example 1.

[0069] Below is taking embodiment 1 as test sample, to the investigation situation of the test of capsule stability. The test samples are stored under the conditions of 37-38°C and relative humidity of 70-80%, and the products are inspected and analyzed under these conditions for 0, 30, 60, and 90 days respectively. The results show that the product quality of the high-efficiency calcium supplement capsule of the present invention is stable.

[0070] Table 6 Stability test of high-efficiency calcium supplement capsules of the present invention

[0071]

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Abstract

The invention provides a high-efficiency calcium supplement capsule and a preparation method of the high-efficiency calcium supplement capsule. According to the specification of 0.45g / capsule, 1000 calcium supplement capsules comprise the following components by weight: 45-55g of calcium carbonate, 126-154g of calcium citrate malate, 108-132g of D-glucosamine hydrochloride, 90-110g of chondroitin sulfate, 18-22g of casein phosphopeptides and 18-22g of vitamin C. The preparation method comprises the following steps of: respectively sieving the D-glucosamine hydrochloride, the chondroitin sulfate, the calcium carbonate, the calcium citrate malate, the casein phosphopeptides and the vitamin C by 80 screen meshes, mixing according to proportion, and filling into a hollow capsule. The high-efficiency calcium supplement capsule provided by the invention not only can promote the absorption of calcium, but also can increase the deposition of bone calcium salt, so that the use of the bone on the calcium can be improved.

Description

technical field [0001] The invention relates to a high-efficiency calcium supplement capsule and a preparation method thereof, belonging to the technical field of medicine and health care products. Background technique [0002] With the increase of age, the bone density of the human body gradually decreases. Many regional epidemiological surveys have shown that from the age of 40, the bone density of various parts of the human body begins to decline year by year, and the decline rate of women in the age group of 50-69 is even faster. At the same time, the incidence of osteoporosis gradually increases with age. Therefore, middle-aged and elderly people are high-risk groups with decreased bone density and susceptibility to osteoporosis. Osteoporosis (Osteoporosis, OP) is a common metabolic bone disease that threatens the health of middle-aged and elderly people. Trauma can cause fracture, which is a state of decreased bone density per unit volume of bone. According to the et...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/14A61K33/10A61K9/48A61P3/14A23L1/305A23L1/304A23L1/302A61K31/194A61K31/7008A61K31/737A61K31/375A23L33/15
Inventor 刘忠华刘文杰杜峰孙桐
Owner SHANDONG CENT FOR DISEASE CONTROL & PREVENTION
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