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Method for preparing ointment for treating lumbar disc herniation

A technology of lumbar intervertebral disc herniation and ointment, which is applied in the direction of medical preparations containing active ingredients, ointment delivery, and pharmaceutical formulas, can solve the problems of large side effects, rebound phenomenon, and inability to eradicate, so as to achieve high morbidity, protect health, and improve The effect on labor productivity

Active Publication Date: 2013-02-20
吉林省东北亚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Similar or similar products in China generally use anti-inflammatory, analgesic, and hormone-based drugs for treatment. Although the symptoms can be controlled to a certain extent, once the drug is stopped, there will be a rebound phenomenon, or even worsen, and the side effects are large, cannot be eradicated, and are easy to relapse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The required raw materials are calculated in parts by weight: 1800 parts of Clematis, 800 parts of Corydalis Corydalis, 800 parts of star anise, 800 parts of bean root, 310 parts of tooth soap, 310 parts of asarum, 280 parts of rubber, and 25 parts of cinnamon oil , 25 parts of borneol, 10 parts of diphenhydramine hydrochloride, 12 parts of methyl salicylate, 430 parts of zinc oxide, 100 parts of rosin, 15 parts of lanolin, 15 parts of petrolatum, and 5 parts of liquid paraffin.

preparation Embodiment 1

[0024] Weigh Asarum 310g, star anise 800g, add 16 times the amount of water to extract the volatile oil, each extraction is 8 hours, and the volatile oil is clathrated with β-cyclodextrin; the grinding method (β-CD: volatile oil 6:1, water: β- CD 6: 1) Grind for 2 hours each time, extract 1800g of Clematis clematis, 310g of tooth soap, 800g of Corydalis Corydalis, 800g of Beidougen, plus 6 times the amount of 60% ethanol with asarum and star anise dregs, and extract three times for 2 hours, combined the filtrates, concentrated to the extract (70°C) with a relative density of 1.10 to 1.20, added 25g of borneol, 10g of diphenhydramine hydrochloride, 25g of cinnamon oil, 5g of liquid paraffin, and 12g of methyl salicylate, and stirred and mixed evenly. It is co-dissolved, and then mixed with 430g of zinc oxide, 100g of crushed rosin, 15g of lanolin, and 15g of vaseline in the prescribed amount, respectively, and mixed with 280g of rubber, and placed in a foam basin for 15 to 20 ho...

Embodiment 2

[0026] The required raw materials are calculated in parts by weight: 2000 parts of clematis, 1000 parts of corydalis, 1000 parts of star anise, 1000 parts of bean root, 333 parts of tooth soap, 333 parts of asarum, 300 parts of rubber, and 28 parts of cinnamon oil , 28 parts of borneol, 12.6 parts of diphenhydramine hydrochloride, 14 parts of methyl salicylate, 451 parts of zinc oxide, 120 parts of rosin, 20 parts of lanolin, 20 parts of petrolatum, and 10 parts of liquid paraffin.

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PUM

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Abstract

The invention discloses a method for preparing ointment for treating lumbar disc herniation, and belongs to the field of preparation methods of medicinal ointments. The ointment consists of clematis root, corydalis tuber and the like. The method comprises the following steps of: preparing beta-cyclodextrin covered volatile oil by adopting a grinding method; extracting clematis root, fructus gleditsiae and the like and residue of asarum and illicium verum for three times and 2 hours every time by adding 6 times of 60 percent ethanol, combining filtrate, and concentrating to obtain extract of which the relative density is 1.10 to 1.20; stirring borneol, diphenhydramine hydrochloride and the like, dissolving, mixing with zinc oxide, crushed rosin, rubber and the like uniformly, and standing for 15 to 20 hours in a rubber soaking basin; and extracting and concentrating the medicinal materials into the extract, mixing the extract, the beta-cyclodextrin covered volatile oil, the rubber and other matrix, thermally pressing to prepare paste, coating, bushing, slicing, and thus obtaining the ointment. The formula accords with the principle of a prescription formula, and the ointment has the effects of diminishing swelling, relieving pain, relaxing muscles and stimulating blood circulation; and the ointment effectively relieves various pains caused by the lumbar disc herniation, rheumatism or rheumatoid, strain or bruise, hyperostosis, cancers and the like.

Description

technical field [0001] The invention belongs to the field of preparation method of medicinal ointment, in particular relates to a preparation method of medicinal ointment which can be used for treating lumbar intervertebral disc herniation. Background technique [0002] Lumbar disc herniation is a series of clinical symptoms and signs manifested by lumbar disc degeneration, annulus fibrosus rupture, and nucleus pulposus protrusion stimulating or compressing nerve roots and cauda equina, commonly known as "lumbar disc herniation". According to clinical statistics, lumbar disc herniation is one of the common orthopedic diseases, and about 1 / 5 of patients with low back and leg pain are caused by lumbar disc herniation. The most common symptom in patients with this disease is pain, mostly manifested as low back pain, sciatica, and typical sciatica. Pain is a subjective symptom produced by the human body after being subjected to noxious stimuli, which always threatens human heal...

Claims

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Application Information

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IPC IPC(8): A61K36/716A61K9/06A61K47/44A61P19/08A61K31/045
Inventor 张辉张洁孙佳明贾静
Owner 吉林省东北亚生物科技有限公司
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