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Preparation method of pullingqianzheng pills

A technology of Qianzheng pills and raw materials, which is applied in the direction of medical preparations containing active ingredients, pill delivery, sugar-coated pills, etc. It can solve problems that affect the application of medicine primers, affect patient compliance, and inconvenient use, and achieve uniform size, Fast-acting, easy-to-use effects

Active Publication Date: 2013-03-06
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In clinical application, it is extremely inconvenient for patients to use: it is not easy to grind finely, which affects the efficacy of the medicine; when the patient has no drinking habit, it affects the application of the medicine primer; the fishy smell of the silkworm and scorpion animal medicine affects the patient's compliance

Method used

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  • Preparation method of pullingqianzheng pills
  • Preparation method of pullingqianzheng pills
  • Preparation method of pullingqianzheng pills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A preparation method of Qianzheng Pills includes the following steps:

[0047] 1) In terms of parts by mass, use 3 parts of white aconite, 3 parts of rigid silkworm and 4 parts of whole scorpion as raw materials, and clean the raw materials to remove impurities; crush and dry the whole scorpion to water mass parts Less than 10%;

[0048] 2) Mix the white aconite, the dead silkworm, and the broken whole scorpion, initially crush (or coarse powder), and then use an ultrafine grinder to crush into a very fine powder, and then sterilize;

[0049] 3) Mix the ultra-fine powder of the raw material medicine with the rice wine suspension in a mass ratio of 3-10:1 to prepare soft materials. The rice wine suspension is a suspension of croscarmellose with a mass concentration of 5% in the rice wine Sodium base cellulose;

[0050] 4) The soft material is made into pellets through the plasticizing method, and then dried at 50-60°C and then coated; after the coating is completed, dried to ob...

Embodiment 2

[0052] A preparation method of Qianzheng Pills includes the following steps:

[0053] 1) In terms of parts by mass, 3.5 parts of white aconite, 3.2 parts of scorpion silkworm and 5.0 parts of whole scorpion are used as raw materials, and the raw materials are cleanly selected and impurity; the whole scorpion is crushed and dried to water mass parts Less than 10%;

[0054] 2) Mix the white aconite, the dead silkworm and the crushed whole scorpion, initially crush (or coarse powder), and then use an ultrafine grinder to crush into extremely fine powder, pass through a 200 mesh sieve, and then cobalt 60 Radiation sterilization;

[0055] 3) Mix the very fine powder of the raw material medicine with the rice wine suspension at a mass ratio of 10:1 to prepare the soft material, in which the rice wine suspension is suspended in the rice wine with a mass concentration of 4.5% cross-linked carboxymethyl fiber Sodium;

[0056] 4) The soft material is made into pellets by the plastic method, dr...

Embodiment 3

[0058] A preparation method of Qianzheng Pills includes the following steps:

[0059] 1) In terms of parts by mass, 3.92 parts of white aconite, 3.84 parts of scorpion silkworm and 4.27 parts of whole scorpion are used as raw materials, and the raw materials are selected and impurity removed; the whole scorpion is crushed and dried to water mass parts Less than 10%;

[0060] 2) Mix the white aconite, the dead silkworm and the crushed whole scorpion, initially crush (or coarse powder), and then use an ultrafine grinder to crush into extremely fine powder, pass through a 200 mesh sieve, and then cobalt 60 Radiation sterilization;

[0061] 3) Mix the ultra-fine powder of the raw material medicine with the rice wine suspension at a mass ratio of 10:1 to prepare soft materials, in which the rice wine suspension is suspended in the rice wine with cross-linked carboxymethyl fiber with a mass concentration of 6% Sodium;

[0062] 4) The soft material is made into pellets by the plastic method...

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Abstract

The invention discloses a preparation method of pullingqianzheng pills, and the preparation method is characterized in that 3 to 5 parts by weight of rhizoma typhonii, 3 to 5 parts by weight of stiff silkworm and 4 to 6 parts by weight of scorpio are adopted as crude drugs, and the crude drugs are sorted to remove the impurities; the scorpio is dried after being broken; the crude drugs are shattered into fine powder through an ultrafine pulverizer to be sterilized; the ultrafine powder of the crude drugs is mixed with yellow wine suspension to prepare softwood; the softwood is prepared into pills through plastic method, and then the pills are coated after being dried under the temperature of 50 to 80DEG C; and the pills are dried after being coated to obtain the pullingqianzheng pills. Due to the adoption of the preparation method, not only can biological active ingredients of the pullingqianzheng pills be maintained, but also the toxicity of the calcium oxalate crystal which is the toxic component in the rhizome typhonii can be reduced. The prepared pullingqianzheng pills hasve the advantages of high treatment effect, small dosage, small toxicity and side effect and convenience in use.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to a preparation method of Qianzheng pills. Background technique [0002] In most literatures and textbooks, Qianzheng San is believed to come from Yang Kuo’s "The Yang Family Tibetan Recipe" of the Song Dynasty, and it consists of three medicines: Baifuzi, Stony Silkworm, and Quanxie. In fact, as early as the Song Dynasty, Sun Simiao's "Thousand Gold Prescriptions" in the Tang Dynasty had the "don't change the golden pill" to treat crooked mouth and eyes, using raw white aconite and rigid silkworm; in the three centipedes, centipedes, araceae, Angelica dahurica and musk; in the book "Danxi Xinfa" by Zhu Danxi during the Jin and Yuan Dynasties, it said: "If you have a stroke, you will have a crooked mouth and eyes, white aconite, rigid silkworm, and whole scorpion, and use them together. Each is divided into equal parts. One money, mixed with hot wine.” I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K9/28A61P25/02A61K35/64A61K35/646
Inventor 同卓斌朱爱华王四旺张芳侠张小艳杨钧
Owner 陕西中药研究所
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