A kind of graft copolymer, its preparation method and layer-by-layer modification material

Abstract

The invention provides grafted copolymer which is provided with a structure represented by the formula (1) or the formula (II). The grafted copolymer has good water solubility and good electrochemistry response characteristics due to the fact that the grafted copolymer is provided with electroactive aniline oligomer segments. Prepared grafted copolymer is adsorbed to the surfaces of materials which are subjected to preprocessing layer by layer so as to obtain the layer-by-layer decorative materials which have an adjustable composite layer number and good electroactivity. The layer-by-layer decorative materials, used as biomedical polymer materials, can be better applied to the field of tissue engineering like artificial organs or tissue repair representing by the formula (1) or the formula (II).

Description

technical field

[0001] The invention relates to the technical field of biomedical polymer materials, in particular to a graft copolymer, its preparation method and a layer-by-layer modification material. Background technique

[0002] Tissue engineering has made great progress in seed cells, three-dimensional scaffold materials, bioactive factors, tissue construction, implantation in vivo, etc., and has good industrialization prospects. The patient's treatment brought light.

[0003] The three important factors of tissue engineering are materials, cells and signals. Scientific issues such as how to achieve the best interaction between materials and cells, and how materials and signals affect cell behavior have become research hotspots. It has been found that modifying and functionalizing the surface of traditional materials can greatly improve and regulate cell proliferation and differentiation. Therefore, various surface modification methods such as laser etching, plasma s...

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