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Medicinal composition with dysentery stopping effect and preparation method thereof

A composition and medicine technology, applied in the field of poultry and livestock medicine, can solve the problems of affecting poultry and livestock egg production, disturbed intestinal flora, unable to be excreted from the body, etc., so as to avoid the formation of drug-resistant strains and have less toxic and side effects. , the effect of reducing residual

Inactive Publication Date: 2014-09-10
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Western medicine antibiotics are fast in stopping diarrhea and have a high cure rate, fewer animals die from dysentery, but the drug residues of feeding antibiotics are relatively heavy. Studies have shown that the drug residues of antibiotics consumed by animals and poultry cannot be excreted, which can easily cause intestinal flora disorder , affecting poultry and livestock egg production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Prescription: Top Ten Contributors 150g Zhishencao 150g Pulsatilla 120g Hawthorn 100g Myrobalan 100g Ginger 100g Pomegranate Peel Charcoal 20g

[0022] Preparation method: Take Shigongong and Myrobalan, add 1500ml of 60% ethanol, reflux extraction twice, each time for 1.5 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30 to 1.35 at 60°C. Dry under reduced pressure and crush into fine powder; take Zhiyuecao, Pulsatilla, Hawthorn, and Ginger, add 4700ml of water, extract twice, each time for 2 hours, filter, combine the filtrates, and when the filtrates are concentrated under reduced pressure to 60°C, the relative density is 1.30-1.35 thick paste, dried under reduced pressure, crushed into fine powder; take pomegranate husk charcoal, crushed into fine powder; take the above three fine powders, add 60g of dextrin, mix well, and dry-press granules to obtain. (theoretical total amount is ...

Embodiment 2

[0024] Prescription: Top ten meritorious service 9kg Zhili grass 6kg Pulsatilla 4.5kg Hawthorn 6kg Myrobalan 4kg Ginger 4kg Pomegranate peel charcoal 1.25kg

[0025] Preparation method: Take Shigongong and Myrobalan, add 52L of 60% ethanol, reflux extraction twice, each time for 1.5 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30-1.35 at 60°C. Dry under reduced pressure and crush into fine powder; take Zhiyuecao, Pulsatilla, Hawthorn, and Ginger, add 164L of water, extract twice, each time for 2 hours, filter, combine the filtrates, and when the filtrates are concentrated under reduced pressure to 60°C, the relative density is 1.30~1.35 thick paste, dried under reduced pressure, crushed into fine powder; take pomegranate peel charcoal, crushed into fine powder; take the above three fine powders, add 5kg of dextrin, 1.5kg of sucrose, mix well, and granulate with 80% ethanol , dried, that i...

Embodiment 3

[0027] Prescription: Top Ten Contributions 1200g Zhishencao 1200g Pulsatilla 1500g Hawthorn 800g Myrobalan 1200g Ginger 1200g Pomegranate Peel Charcoal 150g

[0028] Preparation method: Take Shibaonggong and Myrobalan, add 19200ml of 60% ethanol, reflux extraction twice, each time for 1.5 hours, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30-1.35 at 60°C. Dry under reduced pressure and crush into fine powder; take Zhiyuecao, Pulsatilla, Hawthorn, and Ginger, add 56400ml of water, extract twice, each time for 2 hours, filter, combine the filtrates, and when the filtrates are concentrated under reduced pressure to 60°C, the relative density is 1.30-1.35 thick paste, dried under reduced pressure, crushed into fine powder; take pomegranate peel charcoal, crushed into fine powder; take the above three fine powders, add 800g of starch, mix well, and dry press granules to obtain. (theoretical total am...

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PUM

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Abstract

The invention discloses a medicinal composition with a dysentery stopping effect and a preparation method thereof, and belongs to the technical field of livestock medicaments. The medicinal composition is prepared from mahonia, majoram, Chinese pulsatilla root, hawthorn, terminalia fruit, ginger, pomegranate husk charcoal and the like serving as raw medicaments, wherein the raw medicaments are treated by water extraction, 60 percent ethanol reflux and extraction and direct crushing respectively according to different properties of the medicaments and prepared into powder or granules. The medicinal composition has the effects of clearing away heat, cooling blood, detoxifying and stopping dysentery, and is mainly used for treating the dysentery of livestock infection.

Description

technical field [0001] The invention belongs to the technical field of poultry medicines, and in particular relates to a pharmaceutical composition with antidiarrheal effect and a preparation method thereof. Background technique [0002] Common clinical dysentery is mainly caused by bacillary dysentery. Bacillary dysentery is referred to as bacillary dysentery. The main clinical manifestations are fever, abdominal pain, diarrhea, tenesmus, and pus and bloody stool. Bacillary dysentery is still one of the frequently-occurring diseases in my country. Shigella is a Gram-negative short bacillus, which is divided into 4 groups and 39 serotypes, and there is no cross-immunity between each group and each type. [0003] Livestock and poultry dysentery is a serious intestinal infectious disease, such as pig diarrhea, piglet yellow and white scour, lamb diarrhea, calf diarrhea, calf paratyphoid, four seasons diarrhea, infectious gastroenteritis, bacterial and viral mixed infection ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P1/12A61P31/04
CPCY02A40/70
Inventor 单虎周传凤杨海燕张乐萃秦志华蔡秀磊张洪亮
Owner QINGDAO AGRI UNIV