A kind of preparation method of high molecular weight medicinal polyvinylpyrrolidone

The technology of polyvinylpyrrolidone and vinylpyrrolidone is applied in the fields of medicine, chemical industry and synthetic polymer, and can solve the problems such as difficulty in meeting pharmacopoeia requirements, difficulty in achieving uniform mixing, increase in energy consumption, etc. Guaranteed quality effect
CN103254338BActive Publication Date: 2016-02-17HUZHOU SHENHUA HIGH POLYMER MATERIAL
8 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HUZHOU SHENHUA HIGH POLYMER MATERIAL
Publication Date
2016-02-17

Smart Images

  • Figure 1
    Figure 1
Patent Text Reader

Abstract

The invention discloses a preparation method of a medicinal polyvinylpyrrolidone with high molecular weight, which belongs to the fields of medicine chemical industry and synthetic polymer technology. The method concretely the following steps: putting water, N-vinyl pyrrolidone (NVP) and initiator into a reaction vessel in order, stirring and heating, generating a polymerization of NVP, after the reaction ends, filtering the polymer fluid, drying and crushing, and obtaining the finished product. The invention has the beneficial effect that, adsorption and ultrafiltration or the like are not needed for refining the polymer fluid, therefore the energy consumption of drying added for greatly dilution of the high viscosity polymer fluid which is used for improving refining efficiency and yield is avoided, simultaneously a lot of waste water generated in adsorption, ultrafiltration and other refining methods is avoided, thereby saving the waste water treatment process matched thereof. The invention employs continuous low temperature drying and crushing, thereby substantially improving production efficiency and protecting the product quality.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a kind of preparation method of polymer, relate in particular to the preparation method of the povidone of composite pharmaceutical specification, more specifically, the present invention relates to the preparation method of high molecular weight, high-purity povidone of composite American, European Pharmacopoeia standard, The invention belongs to the technical field of medicine chemical industry and synthetic polymer. Background technique

[0002] PVP is widely used in pharmaceutical production as a pharmaceutical excipient (Povidone, namely Povidone). The pharmacopoeias of various countries, especially the current pharmacopoeias of the United States, Europe, Japan, etc., have quality standards for povidone, especially for the impurities N-vinylpyrrolidone (hereinafter referred to as NVP), 2-pyrrolidone, formic acid, aldehydes, peroxides, There are strict requirements on the content of hydrazine, etc., and no other ad...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More